It Looks Like Flexibility but Acts Like Stress – Why Hypermobility Can Disrupt Sleep, Anxiety, and Healing | Sleep | E114
23 Jan 2026 · 5 min
Aaron Hartman explains how hypermobility, which looks like flexibility, can trigger dysautonomia, anxiety, and sleep problems when dysregulated by mast cell activation, mold exposure, or poor nutrition. Hypermobile people often have larger cerebellums and faster reaction times but face higher rates of POTS and neurodivergence. Treatment focuses on diet, environmental remediation, and nutrients like vitamin C and thiamine.
Chapters
If you're hypermobile, you're super flexible and you're a baseball player, you actually have a slingshot for an arm and you can throw a baseball faster. If you have hypermobility, you actually tend to have a bigger cerebellum. If you train it, you become more skilled and more coordinated. People with hypermobility have quicker reaction times, easier startled, which is the negative side, but quicker reaction times. So they can actually make them better at certain athletic issues. But the problem is is dysregulated hypermobility, which if you have mast cell issues or poor nutrition, poor diet exposure, environmental chemicals and toxins, maybe you've got mold, which is inflammatory or Lyme. Lyme really loves connective tissue, particularly connective tissue that has low oxygen tension. All of a sudden this hypermobility can set you up for a whole host of other things. Would you like to know something I've discovered that is something you probably never heard about being a connection between mold or language building illness, sirs, Chronic inflammatory response syndrome and dysautonomia, POTS and other chronic issues and trauma and autism and being neurodivergent. Here we go. If you have this thing, you are 400% more likely to be neurodivergent. What is this mystery thing I'm referring to that actually, depending on what you read, 20% of kids have, 15% of college adults have. What I'm referring to is hypermobility. Hypermobility spectrum disorder. Some people refer to it as heds. I like the word hypermobility because it actually can be a superpower for some people. If you're hypermobile, you're super flexible and you're a baseball player, you actually have a slingshot for an arm and you can throw a baseball faster. If you have hypermobility, you actually tend to have a bigger cerebellum. If you train it, you become more skilled and more coordinated. People with hypermobility have quicker reaction times, easier startled, which is the negative side, but quicker reaction times. So they can actually make them better at certain athletic issues. But the problem is is dysregulated hypermobility, which if you have mast cell issues or poor nutrition, poor diet exposure, environmental chemicals and toxins, maybe you've got mold exposure which is inflammatory or Lyme. Lyme really loves connective tissue, particularly connective tissue that has o low oxygen tension all of a sudden this hypermobility can set you up for a whole host of other things. The reason I'm mentioning this is because many of my patients who have sers, Chronic inflammatory Response syndrome, chronic Lyme pantis, pans, autism, you know, a whole host of things. When you're examining them, you'll notice their skin feels kind of soft and velvety. You'll notice that they're, I can't do it. You notice their thumbs can actually touch here or their pinkies. See, my pinky goes here. The pinkies will go back 90, 90 degrees or you'll know their knees kind of go back, go back or. When I was younger I used to be able to do cool tricks. This is one of the ones that happens often. I was, when I was younger I could pop my shoulder out or I could turn 180 degrees or I could w sit or you know what, I put my foot behind my head. I can't do it anymore because I'm older and I'm kind of stiff and tight. But the hypermobility is very, very common. And because of how your fascia relate with everything else. So for example, 80% of the nerves that innervate your fascia, your connective tissue, are sensory, meaning they're giving input back to your brain, back to your nervous system. If you're hypermobile, your tissues are loosey goosey or stretchy, all of a sudden you're giving your nervous system more information about your body, which if you're a high performance athlete could be great. But if you have, you're not and you have nutrient deficiencies and other kind of things going on, all of a sudden your brain can get a low grade trauma, a low grade overstimulation that over time builds and builds and builds and creates this low level anxiety, this hyper alertness, Easily startled wake up middle night and you're like, I can't get back to sleep. If someone gets you anxious or revved up, it's so hard to calm back down. And unfortunately because of those things, sometimes people will use stuff like marijuana drugs, alcohol, even things like medications like benzodiazepines to calm down their nervous system, which strangely enough, benzos actually are a mast cell stabilizer. In some hypermobile individuals, if they use benzos will notice an unusual amount of like they'll feel really, really good because they're calming down their tissue inflammation as well as blocking some of this overactivation of the nervous system related to their hypermobility from mast cell stuff and other things. So the point is that if you're dealing with any chronic health issue, you know, you might be hypermobile and all of a sudden you know, the American diet, the standard American diet, which is nutrient deplete which doesn't have enough vitamin C. Trace minerals, rare earth minerals, B vitamins. One of the interesting things about having your nervous system revved up a little bit is that just the way your adrenal glands work, they actually one of the nutrients they need lots of vitamin C to make stuff. And interestingly enough, vitamin C is the one of the key nutrients in connective tissue disorders. You know, we know scurvy is severe example of vitamin C deficiency. We still recognize now that different dental issues and easy bruising and bleeding and poor wound healing and poor joint and other healing in hypermobile individuals revolves around some of their difficulty making collagen and low vitamin C can play into that.
Have you ever lost trust in your own body or in the doctors who were supposed to help you heal? It happens to millions of people who are stuck in the cycle of prescriptions, tests and and more questions than answers. That's why Dr. Aaron Hartman wrote his new book Uncurable. As a physician and a parent, he's lived through the pain of being told there's nothing more we can do. But instead of accepting that, he built a new path. One that combines traditional and functional medicine to uncover what's really driving illness. Uncurable is more than a book. It's a roadmap to help you find the root causes your doctor might have missed, reactivate your body's natural healing systems and finally believe in what's possible again. If you've lost hope or trust in the system, this book will help you take back control. Go to UncurableBook.com and grab your copy along with Dr. Hartman's free resources to help you start your healing journey today.
So all of a sudden your nutritional stats, Are you eating real food? Do you live in a moldy building? A water damaged building? If you're getting your body loaded with toxins and you don't get enough nutrition, all of a sudden you're going to be more prone to inflammation and a bunch of things related to that, chronic infections like Lyme, bartonella. It's really interesting, Bartonella, one of the things with bartonella, it does cause some weird neurological issues and it's more associated with people with pots and dysautonomia. You know, to date all of my BART patients have been hypermobile, strangely enough. So something to think about. But all of a sudden you're this thing that actually could be a superpower. You're smarter, your brain works a little faster, you have a faster response time. In athletics, you can be a little better athletics. If untrained you can be more clumsy if your cerebellum's bigger and you have your arms a little longer and you're kind of don't have control of your body, all of a sudden you don't have quite the same level of balance and coordination. This thing that could be a superpower and help with intuition. I've noticed in a lot of my patients that are empaths that have this emotional intelligence that they can actually meet someone and get a feel for them really quickly. Are you an honest, dishonest person? Do I like you? Not like you? Like their gut feeling. That intuition is much that gut feeling, intuition is much, much more adept and more higher level of intelligence. Emotional intelligence in that world can be trained and utilized. Or if you have a traumatic life event, sexual, physical, emotional abuse, all of a sudden that impact, that ability for you to feel emotions becomes a weakness. And so understanding if you're hypermobile and if you're neurodivergent, how your environment can play a part in if you have mold issues, if you have Lyme, if you have biotoxin related issues, if you have autoimmune problems or gut health issues. So all of a sudden, connective tissues, it's all your issues and your tissues. I think I heard someone say that kind of cheesy phrase a while ago, but it's really true. In the connective tissues, your connectome, if you want to call it that, hold mast cells, hold a lot of other, you know, the connective tissues hold everything in place, but they also have lots of neurons and ultimately, you know, connective tissues, collagen. If you look, if you do look at tissue, tissue under slides, you look at your heart under a slide or your kidneys or anything. The thing that's holding all that stuff together are your connective tissues. So it makes sense how if they're not quite maximally integral, that could play out into a whole host of other health conditions. And I personally think one of the issues we're seeing more chronic health issues is because we have this very common thing. And on top of that, we're now giving people nutrient deficiencies. One interesting book I read by Dr. Launders, it was thiamine deficiency, dysautonomia and high calorie malnutrition, I believe was the name of the book by Dr. Laundries, who's a pediatrician at Cleveland Clinic. And one of the things that he noticed was a lot of individuals were having like, not gross thiamine or B vibrant deficiencies, but low level ones. And all of a sudden my mental stressors would induce a beriberi like which is a old school disease that doesn't exist anymore, but actually it's kind of everywhere like everything else is, you know, low level B deficiencies. And so when the people are stressed and their need for thiamine goes up, all of a sudden their dysautonomia flares. And strangely enough using high doses of thiamine can actually be used to treat that. The point is, a lot of these weird unrelated things are everywhere and having someone that can help connect those dots for you can be super helpful. But also you need to take charge of health a little bit as well. And if you're hypermobile, you have some issues with your tissues, then diet, environment, exercise, self regulation, having a self regulatory practice, certain nutrients, all these things become super super important. I've put a lot of blogs about this stuff already, but I wanted to mention it here in light of mold related illness or chronic inflammatory response syndrome because it's one of the overlooked things that people don't give credence to being a big deal. That is a big deal. So anyway, I hope this information was helpful. If so, like share, subscribe. We'd love your questions as well if you have additional questions about things and hopefully this information was helpful. Otherwise, take care and we'll talk to you soon.
If you've lost trust in your body or in the system that was supposed to heal you, don't give up. Dr. Aaron Hartman's book Uncurable will help you rediscover what's truly possible. Visit UncurableBook.com to get your copy and start your healing journey today.
More from Aaron


Medical Gaslighting Doesn’t Stop in the Exam Room: How to Trust Yourself and Build the Right Care Team with Dr. Efrat LaMandre | E186


POTS and Dysautonomia: Could Nervous System Dysregulation Be Why You’re Still Sick? | E185


Best of: How Adopting a Child with Special Needs Led to a Medical Revolution | E184


Hypermobility and Fascia: Could Your Connective Tissue Be Why You’re Still Stuck? | E183


Best of: The Classroom Is Failing Our Kids – The Surprising Truth About Neurodivergent Learning with Dr. Roseann Capanna-Hodge | E182


Mast Cell Activation Syndrome: The Hidden Trigger Behind Food Reactions, Fatigue & Chronic Symptoms | E181


Best of: Are EMFs Making You Sick? – Environmental Sensitivities Explained with Dr. Neil Nathan


Could Lyme Disease Be Why You’re Still Sick? Symptoms, Testing, and What May Be Overlooked | E179


Why Your Child Is Dysregulated: Nervous System Regulation, Screen Time, and the CALMS Protocol with Dr. Roseann Capanna-Hodge | E178


Mold Exposure May Be Why You’re Still Sick: The Hidden Connection to CIRS and Chronic Inflammation


Best of: CIRS and the Bio Toxin Pathway: A Deep Dive into Detoxification and Healing with Dr. Jenski