Amanda explains why triglycerides can spike when you're losing weight on a low-carb diet or intermittent fasting. The liver releases more fat particles into the bloodstream as it mobilizes stored fat, which can temporarily raise triglyceride levels even though you're burning fat.
Amanda, can you explain what might cause triglycerides to elevate even with intermittent fasting? Low carbs. So triglycerides, remember, triglycerides do not move around on their own. Triglycerides are carried on lipoproteins from the liver, particularly VLDL and ldl. Why might that go up in someone who's low carb? It could be because they're losing weight. That is a very well known, very established phenomenon where during active weight loss, a person will have what is sometimes referred. I'm actually thinking of a specific title of a manuscript where it refers to a transient hypercholesterolemia of weight loss. In fact, Stephen Finney published that paper, if I remember correctly, him being one of the godfathers of the modern kind of ketogenic diet movement. So when, if someone's actively losing weight, it's not surprising that they're. They're relying more on fat for fuel. And the liver is attempting to help that meet that demand by making more triglycerides and releasing it. And it's not a worry. That's a fat that's just going to get burned. Burned by the muscle, primarily. So, yeah, weight loss will result in an acute increase in triglycerides and basically you could count on that lingering until the weight loss stops. So it's something that can continue for quite a. For quite a while. But also HDL is going to be going up, so it's generally going to be a pretty favorable change. Or even if triglycerides are high or staying high, HDL can come up too.