Nobody Taught You THIS About Sex

7 Aug 2025 · 38 min
Episode

7 Aug 2025 · 38 min

0:00

In this episode Bryan Johnson hosts a candid conversation with sex‑researcher Kate Tolo and clinician Dr. Mike Mallon about the science of sexual activity, its health benefits, and the hidden risks of modern sexual practices. The discussion opens with the hosts’ own anxiety about discussing taboo topics and the cultural silence that leaves many young people uninformed. They then outline robust evidence that regular sex functions as exercise, reduces cortisol, boosts oxytocin and endorphins, lowers depression risk, enhances immune IgA, reduces prostate‑cancer risk in men, and correlates with lower all‑cause mortality and improved sleep. The role of orgasm and anatomical differences (clitoral vs penile stimulation) is highlighted, noting that most women need clitoral stimulation for orgasm. The conversation shifts to risky practices: breath‑play/choking is linked to elevated S100B, a biomarker of sub‑clinical brain injury; anal‑to‑oral contact (rimming) can transmit a wide range of bacterial pathogens and increase urinary‑tract infection risk, prompting a detailed six‑step hygiene protocol. A study of 75 HIV‑negative men shows gut‑microbiome signatures that differ by sexual role (insertive, receptive, versatile) and associate with distinct nutrient‑metabolism pathways. Nighttime erection episodes are presented as a vital health metric comparable to blood pressure, with devices like Adam Sensor measuring male erections and emerging research on female arousal cycles. The hosts criticize reliance on pornography as the primary sexual education source, argue that many risky practices lack safety testing, and propose a holistic “operating manual” that integrates sleep, nutrition, exercise, testing, and hygiene to protect sexual health. Throughout, they emphasize empathy for listeners, encourage proactive health monitoring, and pledge to continue exposing taboo subjects.

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