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In this Longevity and Lifestyle podcast episode, host Claudia von Boeselager interviews Dr. Molly Maloof, a physician, Stanford instructor, technologist, and entrepreneur. Dr. Maloof explains how social connection and love are fundamental drivers of healthspan, linking mitochondrial function, oxytocin biology, and metabolic regulation. She describes mitochondria as "social organelles" that integrate stress responses and fuse/fission in response to relationship quality, arguing that poor relationships deplete cellular energy and promote inflammation. The conversation covers the impact of adverse childhood experiences and chronic psychosocial stress on cellular methylation of oxytocin receptors, and how this contributes to obesity, trauma, and disease. Dr. Maloof discusses psychedelic‑assisted therapy, especially MDMA, as a way to reopen critical periods of social reward learning, and reviews other trauma‑healing modalities such as somatic experiencing, EMDR, tapping, and narrative work. She shares personal anecdotes about weight gain during pandemic isolation and the restorative power of reconnection. The episode also details her entrepreneurial venture: an education platform and consumer‑product line that teaches mitochondrial health, relationship skills, and responsible psychedelic use, including a forthcoming Stanford‑based course that participants can also teach. Throughout, she emphasizes that love and trust (mediated by oxytocin) are “nature’s medicine,” protecting mitochondria, reducing inflammation, and enhancing cardiovascular and metabolic function. The discussion ends with a call to spread love, sign up for a newsletter, and consider community‑level interventions to combat deaths of despair.

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