51:03

In this Longevity and Lifestyle podcast episode, host Claudia von Boeselager interviews John Gillen, a former jockey turned addiction‑treatment innovator who introduced NAD+ (nicotinamide adenine dinucleotide) therapy to Europe in 2010. Gillen recounts his 2009 discovery of an IV NAD+ protocol at a clinic in Tijuana, Mexico, where he observed rapid physical, emotional, and cognitive recovery in alcohol‑dependent patients. He explains that chronic alcohol use depletes NAD+, leading to severe withdrawal and a pellagra‑like syndrome, and that restoring NAD+ supports detoxification, neurotransmitter balance, and cellular energy. Gillen describes the challenges of bringing NAD+ to the UK, including regulatory hurdles with the CQC and public skepticism, and details his clinic’s evolution from Bionad in Harley‑Street to broader clinical work. He discusses dosing nuances, the “NAD dump” phenomenon, and side‑effects of IV infusions, advocating sub‑cutaneous (home) administration as a more tolerable, cost‑effective alternative. The conversation expands to NAD+’s potential in neurodegenerative diseases, the importance of maintaining the NAD/NADH ratio, and the limited efficacy of over‑the‑counter precursors. Gillen also covers his work with photobiomodulation, the launch of Scotland’s first psychedelic‑assisted ketamine clinic (Eulis), and the integration of NAD+ with ketamine for treatment‑resistant depression and early‑stage dementia. Practical advice is offered for home use, lifestyle factors that deplete NAD+, and how to choose quality compounds. Finally, Gillen shares commercial ventures—NAD+ for pets (NADPet) and equine performance—along with resources, training programs, and online platforms for clinicians and the public interested in NAD+ and psychedelic therapies.

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