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In this segment, Dr. Dale Bredesen (Speaker A) uses a personal anecdote about undergoing colonoscopies on Valentine's Day to introduce the concept of a "cognoscopy"—a simple, routine cognitive screening. He argues that cognitive decline, traditionally seen as a disease of the 60s‑80s, actually begins in the late 30s to 50s, but diagnosis is typically delayed by about 20 years. Consequently, he recommends that anyone aged 45 or older should undergo a cognoscopy to detect early signs of decline and intervene before significant impairment occurs.

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