Why experimenting on ovaries holds the keys to increasing the lifespan of humans #shorts #menopause

Name: Why experimenting on ovaries holds the keys to increasing the lifespan of humans #shorts #menopause
Uploaded: 2023-05-22T14:00:09+00:00
Duration: 50 s
Channel: Claudia von Boeselager
Description: In this short monologue, the speaker proposes that ovaries function as a natural "time machine" that reflects accelerated human aging, offering a unique…

22 May 2023 · 1 min

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In this short monologue, the speaker proposes that ovaries function as a natural "time machine" that reflects accelerated human aging, offering a unique human model for testing longevity and health‑span interventions. While current longevity research relies on animal models such as monkeys or dogs, or on cell‑based systems, the speaker argues that women in their 30s could be enrolled in clinical‑style trials where simple, non‑invasive measurements—pregnancy status, bone density, hormone levels—serve as proxies for overall bodily aging. This approach would allow rapid, human‑relevant assessment of interventions that aim to extend healthspan.

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Ovaries are so interesting. If you think about it, it's like a time machine. Ovaries give us inside of a human, a model for accelerated human aging. There's so much interest in the longevity space on trying to find interventions that will extend healthspan. One of the big elephants in the room is how do we test those longevity interventions? Right now we use animal models or cell-based models, and I think the best animal model we have right now is either a monkey or a dog. But ovaries give us the opportunity to test interventions in a human model. You can imagine doing clinical trials for longevity or healthspan interventions that use women in their 30s with really measurable endpoints, things like pregnant, not pregnant, measuring things like bone density and hormone levels, really not very invasive things to monitor ovarian health, which is then a proxy for aging in the rest of the body.