#94 How Data Science Enables Better Decisions at Merck
4 Jul 2022 · 40 min
Suman Giri, Global Head of Data Science at Merck, explains how AI accelerates drug discovery, clinical trials, and manufacturing. He describes three COVID cases where models accidentally learned demographic bias, and outlines Merck's governance framework to catch it. The biggest challenge: fragmented data across 60+ countries and limited access to patient records.
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You're listening to Data Framed, a podcast by Data Camp. In this show, you'll hear all the latest trends and insights in data science. Whether you're just getting started in your data career or you're a data leader looking to scale data driven decisions in your organization, join us for in depth discussions with data and analytics leaders at the forefront of the data revolution. Let's dive right in.
Hello everyone, this is Adele, Data Science evangelist and educator at datacamp. A few episodes back we had Current Cats on the podcast discuss how data science is transforming healthcare. A lot of the themes that emerge in the episode is that while there are incredible gains happening on the research side, there are many ways data science is moving the needle in improving health outcomes today. This is just as much the case in pharmaceuticals today, and this is why I'm so excited to chat with Sumanjiri on today's podcast. Sumanjiri is the Global Head of Data Science of the Human Health Division at Merck. He's held a variety of data leadership roles throughout his career and has a PhD in Advanced Infrastructure Systems from Carnegie Mellon University and throughout the episode displayed incredible insights when it comes to the state of data science and pharmaceuticals. Throughout our chat we talked about how data science is transforming the pharmaceuticals industry today, the main data science challenges facing pharma organizations, data interoperability and data ethics how to approach data culture. The right skill makes for data teams and more. If you enjoyed this episode, make sure to rate, subscribe and comment, but only if you liked it. Now let's dive right in.
Suman, it's great to have you on the show.
Thanks for having me.
I am excited to talk to you about data science and machine learning and pharmaceuticals. Your experience leading data science at Merck and more. But before, I'd love to learn about your background and what got you into the data space.
Yeah, sure. So my name is Suman Giri. I head Data Science at Merck Human Health, Merck as you know, is one of world's largest pharmaceutical companies. We have world leading products in the oncology, vaccines and cardiovascular space. So in my role at Merck, I'm responsible for all of the commercial analytics, Data Science and MLOps that takes place for our early stage, advanced stage and inline products. And my background is in mathematics and engineering. I did my PhD from Carnegie Mellon where I researched machine learning algorithms in the energy efficiency space and since then most of my career has been spent in different healthcare related companies. So I work in payer organizations, payer providers, health tech and as of a year ago I started my new role in Merck. I landed in data science just by the virtue of my education, which is what I studied. So it was easy for me to just do that as a profession. I landed in healthcare a little bit by accident, one of the areas I was curious about and somehow one thing led to the other and I was like fully immersed in the healthcare experience.
So to start off our conversation, given your experience as a data leader in pharmaceuticals and healthcare, I'd love to understand the current state of data science and machine learning in pharmaceuticals. Arguably the pharmaceutical space and healthcare overall is the most exciting space for data science because of the potential value data science and machine learning applications can provide in this space. Given your experience as a data leader in pharmaceuticals, I'd love to understand how you would describe what the landscape of data science and pharmaceuticals looks like today and how it has evolved over the past few years.
I think the major fields within pharma where data science gets used are drug development and discovery, diagnostics, clinical trials and manufacturing and supply chain and commercial and regulatory processes. So these are kind of the major areas. But to give you a sense of where maybe the impact is, we can start with COVID right? Especially around MRNA vaccines. There was a strong role that AI played in accelerating the discovery and deployment of COVID vaccines. Then there was the alphafold announcement this past year from DeepMind, which basically solved the problem of protein folding and is going to accelerate drug discovery significantly. We're also seeing some interesting use cases in the clinical operations like selection of optimal patients for clinical trials, compound screening to test in pre clinical trial, and then there's a commercial space, which is where I sit, where we're seeing a lot of advanced machine learning being applied for effective engagement and promotional marketing for inline products. Finally, there's also some neat applications and potential on the reimbursement side with partnerships with payers for value based outcomes and similar things. So a lot of interesting things happening in the space.
And to get a sense, there seems to be developments within the research space that you see today, like AlphaFold, as you mentioned, a lot of the different innovations that you see, but also developments on the commercial side and applications of machine learning and data science. What are some of the main areas of value you've seen data science and machine learning push the envelope forward for organizations today working in the pharmaceutical space?
Yeah, this is a tough one for me to pick because I think the envelope is being pushed in all directions and everywhere you look like people are doing amazing stuff using applications of data science and machine learning. But if I had to pick one, I would go back to the drug trial space because that's been eye opening for me as somebody relatively new to pharma, because the implications to patient safety are huge. So in drug trials we're seeing intelligent patient selection based on multiple data sources and more targeted criteria, sometimes even using biomarker or genetic information. We're also seeing automation of a bunch of preclinical quality control steps using AI and machine learning, which again we saw during the COVID vaccines. We're also seeing applications of Internet of things slash IoT and real time patient monitoring for patients in active trials, which helps avoid adverse events proactively. And then this area of event adjudication, as it's called in clinical trials can reduce the time to market for a drug significantly. So it has huge implications from just our innovation standpoint. Then there's a lot of interesting work done around simulations on pre trial compounds, using data from similar molecules and known effects to understand adverse implications before the molecule even reaches trial. Right. So this enhances patient safety significantly. And finally, I'll be remiss if I didn't mention how quickly the pharma industry was able to manufacture and distribute the vaccines for Covid. And a lot of that logistics in supply chain was enabled by data science and machine learning. So I think this is the space that I would pick to answer your question, just because you forced me to pick one, because I could just as easily go on about the other areas where something like this is happening as well.
That's really awesome. And I definitely want to expand into the research areas that you discuss here, especially with COVID vaccine. That's a very interesting topic to expand upon. But interestingly following up on your last point here around supply chain optimization and kind of innovation there, when we hear a lot of use cases and of data science and machine learning in pharmaceuticals, in the media, especially in popular discourse, we always talk about drug discovery, these awe inspiring use Cases related to drug discovery algorithms. Right. But there are also a lot of operational aspects where data science can have a lot of value and kind of accelerate the value for patients and improve patient quality of life. You mentioned here, supply chain and clinical trials operations. Do you mind expanding on that area? Go deeply a bit in some of these use cases as well as your experience how you've seen like that value manifest for patients.
So you're absolutely right. Most people when they hear, let's say machine learning and pharma, they think of drug discognizing and maybe one day we'll get to a stage where algorithms can predict the efficacy of a molecule in humans without having to go to trials. But until then, there's a lot that happens in between where algorithms come both to enhance efficiency and productivity. So I already talked about clinical trials and how machine learning is already enhancing patient safety. Data science also has a role to play in understanding like the diseases we want to treat. Like that's the first step, Right. There's a huge play there, the prevalence of such diseases, just to make sure that there's a financially viable model for drug development and distribution. There is a strong role data science plays in creating personalized medicine strategies and accelerating the way we design and develop new drugs for inline products in the commercial space. There's a lot of sophisticated data science that takes place today, especially as it pertains to forecasting, calculating the effect of promotional marketing, reviewing promotional content for compliance and then competitive threat analysis is a huge one. Right. From a commercial standpoint, to understand, let's say that the sales and marketing efforts should be focused and then just creating personalized engagement strategies for healthcare professionals to make them aware of the drug and its benefits. Then there is also use cases like AI driven planograms that help improve productivity, automated data matching, promotional response modeling, rare disease patient finding, et cetera, where machine learning is heavily leveraged. So basically that's a quick preview of the areas apart from just right out clinical drug discovery, where machine learning plays an important role.
And in terms of kind of operationalization, given the machine learning research area is very much so still relatively in research phase. A lot of this is still in some sense ideation. Do you see that a lot of these use cases are actually operationalized today within the pharmaceutical space and they're actually delivering value for pharma companies today?
That's a great question. So this is a framework that I look at it with. Right. So there are companies where data science is the core product. Take Uber as an example. Yes. On its surface it's an app, but everything you do in it has been facilitated by some algorithm that works on data, which inevitably becomes the product that we use. So in those companies is where this relentless push for maybe productionalization comes into play. Then there's a second tier of companies maybe where you are dealing with real time data. So maybe companies like Walmart or Target, where the data is coming in every split second and somehow you need to make intelligent decisions in real time. And then there's a third category of companies which I think is where we sit, which is data science is not part of your core product, but it is a decision support tool, right? So our core product is obviously like the medical drugs that we manufacture, but design, discovery, ideation and distribution of it is enabled by data science. Now, in this context and in this framework, there are maybe models that don't necessarily meet the criteria of full blown, let's say, production, but they're just, let's say, dashboards that have some intelligent component to it that is helping somebody make a quick decision. Or maybe there are questions that somebody has that AI helps them or machine learning helps them get to some sort of strategy around. What I'm trying to say is I think these kind of models and algorithms also have a place, even though they might not be in what would be considered, let's say, production in the traditional tech sense. At Pharma, I've seen a lot of this gets leveraged primarily because we have the luxury of making decisions in batch mode, right? Like we don't have to make decisions in real time all the time. But having said that, there's obviously a class of models, especially in the commercial space, where perhaps the considerations of safety and efficacy are a little bit less nuanced. That's where a lot of the models are in production. So areas like Next Best action, right, where we are enabling sales reps and marketers to come up with the optimal engagement strategy. These are models that I've seen being full production mode, using a pretty sophisticated MLOps architecture. And I'm sure there are parallels around media mix modeling and then salesforce optimization, et cetera. So there are other models that are in production as well. So it's a good mix of models that are maybe slightly ad hoc or one time in nature versus models that are in full blown production.
I love how you cross section the nature of the product you serve with a degree of operationalization needed for that segueing here. I'd love to deep dive much more into the challenges of working in data science and machine Learning in the pharmaceutical space. What would you say are the biggest challenges that are specific for data science in the pharma industry?
So the biggest challenge is around data and it gets worse as you move outside of the US because we are a global company, we operate in more than 60 countries and data gets increasingly sparse and hard to access as you go outside of the US and without data, you have no way to identify the prevalence of a disease, no way to know whether a molecule is financially viable, and no way to even market it effectively. Today, the pharma industry relies on a lot of syndicated data, but the lack of ability to bring simple data sources like claims and ehr. Right. As a simple example, holds us back. Forget about biomarker and genetic information, like that's a whole new level of complexity. But we are struggling to do even the basic things. Over the past few years, there's been some interesting innovation in the space. There's companies like datavant that they're trying to bridge this gap. But I think it's still early days in this space. I do believe that there's a real opportunity here for solutions in data de identification and synthetic data generation and federated learning to accelerate data science and pharma significantly. Having said that, I do think that the regulatory infrastructure needs to evolve in tandem as well to allow for this kind of innovation. Obviously, since we're talking about challenges from a pharma side, we also have a hard time recruiting the right talent, which is associated with data science and pharma. I think there's also a third challenge, which is mindset. Right. So data science by definition has the word science in it. So it requires a little bit of cultural shift in how you think about our processes. And then this is true for healthcare in general, I would say. Right. I found it difficult to do effective change management with the consumers of data science. So just to maybe quickly summarize, I think data talent and culture is how I would describe the bigger challenges in data science and pharma.
That's perfect. So let's expand on these one on one. You know, when thinking about some of these obstacles, let's take for example data, right?
Collection, interoperability, collection, access. What needs to change so that data.
Science innovation here in pharmaceuticals accelerates? Is it regulatory innovation, as you mentioned, as key part of IT industry centers that need to to evolve.
What do you think?
What needs to be unlocked here to be able to push the envelope forward.
When it comes to data? So great question. Again. I obviously talk about data access and interoperability. It's an active area of. I think innovation in pharma is how I would characterize it because everybody knows it's a problem and everybody knows that that's where the bottleneck lies. But I've seen a few major efforts in this field that I personally find exciting. Right. So there are pharma companies that are now beginning to collaborate on sharing anonymized clinical trial information. Some companies have platforms where researchers can go in and submit their molecules and then there are algorithms that score to them on their potential and in the interest of maybe decentralized kind of data sharing and then collaboration. So basically we need more of this. A tidal collaboration between companies, CROs, which is the clinical research organizations, academia and the government. I think the regulation and innovation are obviously two opposing forces by design. So there'll always be a push and pull. And issues like data privacy are extremely important. But I think there's still a wide gap between what we should be able to do to improve lives and what we are able to do today just because our regulatory infrastructure hasn't caught up. So there definitely needs to be a case for a close examination of what are the hurdles from a regulatory side that are preventing us from doing what we supposedly should be able to do. And there's probably some startups in this field that we'll see, or maybe some changes in this field that we'll see prop up in the next few years. And again from a data side, I mentioned data vant, but there's probably a bunch of other space here that can be taken by innovative companies who can enable easier access to data. Not just pharma data, but also, let's say, social determinants of health and publicly available data that can also guide sound decision making. Especially an area or timeframe like right now where there's a bunch of environmental factors like Covid is still a thing. There is like geopolitical considerations today with all of the wars going on, et cetera. So all of these data will somehow inform some sort of strategy. And I think just having some way to access that in an easier fashion so that research and innovation can take place is going to be key.
You mentioned here. When it comes to the data privacy and the applications of data science in pharmaceutical and healthcare in general, a major.
Obstacle to data science and healthcare is bias and ethical use of AI.
I'd love how you can evaluate the risk of harmful outcomes of machine learning and AI and pharmaceuticals and how you.
Go about minimizing it, especially when having this regulatory discussion, to be able to create that data Access, Yes.
So this is something I spend a lot of my time thinking about. Right. So I'm maybe just going to quickly share three examples with you that I learned about recently that I've been thinking about a lot. And this is all data science work related to Covid. And the reason I'm sharing this is just to highlight how big of an issue this is and how underreported and underthought this area is. So, number one for Covid, there was a group of researchers who used chest scans of children who did not have Covid as examples of non Covid cases. And their intent was probably to identify Covid using chest scans. But what the algorithm learned was how to identify children from adults and not Covid. But these are models that made it to a publication stage. So, like, because there was no framework for, like, ethical use or bias measurement in place, this was able to sit through the cracks, so to speak. There's another research where they used chest scans taken while patients were lying down and while they were standing up. Right now, patients who are lying down are more likely to be sick. So what the AI in turn learned was to predict risk from their position and not their actual risk. So again, another example where maybe the intention was right, but because the framework wasn't there to look through, the downstream consequences, ended up doing the wrong thing. And then the third example I'll share with you is an example of an algorithm that was found to pick up on the text font that. That certain hospitals used to label the scans. Right, because they were probably doing OCR and then they were doing a bunch of things around it like image recognition and whatnot. But at the end of the day, the hospitals that had more serious caseloads and the fonts associated with them became predictors of COVID risk and not actual Covid risk. So these are kind of three examples that just elucidate, like, how there are real issues with relying exclusively on algorithms without considering the biases in data. Right. So to mitigate this, at Merck, we closely tie ourselves to what we call the good governance framework. Before we push a model in production, we check for explainability, fairness, robustness, transparency, and privacy, which we believe to be the major pillars of ethical use of data and algorithms. We basically, in tactical terms, we have a debiasing layer that gets applied throughout the model life cycle from data to model to model. So we're not causing any inadvertent consequences. But this is obviously not the final form of it. We have an ongoing partnership with Carnegie Mellon University where we Continue to research ways to understand the downstream implications of heterogeneity in our data and models. So all of this is just something we think about very seriously and we are continuing to iterate in our approach to make sure that we don't end up being the fourth example on this list that I just shared with you.
That's really awesome. And it really elucidates how a lot of this research and a lot of these applications that are exposed to have these bias and these issues really stem from a great place, right? This is a use case of great intention, but can be very harmful downstream if a lot of the bias in your data is actually biased that comes from gender or racial attributes or any of that type of demographical data. And I'd love to unpack even further. What do you think needs to change on the data pre processing side and kind of the data collection side to be able to unbiase a lot of this data?
I think that the premise, right, so there's always going to be bias in the data. As long as there is some sort of, let's say, variance in your data, there's always going to be bias. So bias is just part of the experience, if you will. Now, I think the right way to do this is to think about this from the get go, right? Like what are the implications of said bias and what are frameworks for us to go out and measure. It is should be part of a data scientist's toolkit from the get go. A lot of the times the data that we deal with has already been collected, so we don't get that voice in the input stage. We're working with, let's say third party data or syndicated data that we purchase. So we have very limited input into how it gets collected. But that doesn't mean that once we have it, we don't get to evaluate it for like inherent heterogeneity in the system and what the downstream implications could be, right? So I think part of it is education. Like it's such a new field that it's not part of our vocabulary. Even like most data scientists haven't taken this class or maybe even heard about this as part of their education. So just education and a solid framework I think is the way to solve this and just constant iteration, right? Like I think this experimentation is part of data science. I think that's what makes it a science. So just fully experimenting and understanding what are the implications of a model that went into production and then touched certain lives and what is the bias that is inherently Built into the whole system I think needs to be an ongoing conversation. I mean to answer your question, Adil, I don't think I have a good answer for what needs to change in the data collection side apart from once at least the data is collected like people should be evaluating it and not just pushing it into a model to modeling exercises. There needs to be a pause and think before you start pushing it into feature engineering or modeling framework.
That's really great. And circling back to the other challenges you mentioned around data science and pharmaceuticals, I'd love to unpack that talent component. And you mentioned here education. So what has been the most challenging aspect of finding the right talent within data science and pharmaceuticals? And what does a great talent profile look like within data science and pharmaceuticals?
So it's a two part question, right? So let me answer the second one because that's the easy one which is what does a great talent profile look like for let's say data science in the pharma industry? So I think the biggest asset a data scientist can have is the good problem solving skills, right? Like forget about data science or the technical aspects. A lot of the times what I find the true value of data scientist in again the third category of companies that I mentioned earlier, which is where data science is primarily used as a decision support tool, is to understand the context in which the decision is being made, right. And then formulate that into some sort of framework that can be maybe improved by use of an algorithm or use of some sort of intelligent automation. Right? So I think problem solving is key component to a high performing data scientist. And then there's aspects of collaboration because usually data science doesn't happen in vacuum and it's not a backend job, so to speak. You have to be continuously iterating with your stakeholders, pushing back on certain things that don't make sense and maybe giving in certain things that are just required as to drive things forward. So just that level of collaboration and communication I think is a second key component. And third is I would say the foundational aspects of data science and machine learning, right? Like things like bias and variance, like things like the assumptions behind like linear regression. Because the problem I see in today's talent is they're so enamored by the fancy stuff, let's say federated learning or deep learning or this or that because they have kind of overlook the fundamentals. And that's again another thing that further perpetuates the biases that we have. What we look for is somebody who has the fundamentals down because the day of a data scientist that just imports like X model and then just applies it is increasingly numbered, right? Especially with auto ML and just the ease of use of certain tools. I think the true differentiator is going to be a data scientist who can frame a business problem in a context that makes sense and drives value and is able to just execute in a collaborative fashion. Now the fourth thing we look for, and this is not true for all the data scientists, but depending on our need, we look for somebody who is heavy on the OP side, right? So the ML ops side. So again as I said, model building is an increasingly kind of productized skill set, right? Like today you could just go and get a data Robot or a H2 or driverless AI or a data IQ and like they will run through all of the models for you, create a thousand different features for you. And it's probably going to be better, barring a few cases than what data scientists can do with the limited set of experiments that they can run. But where a data scientist is going to be needed is to take that model and put it in into some sort of workflow that makes sense for the business. So this will include components like model governance, like are you checking for drift in your data, right? Is this integrated into whatever APIs the end user platform reads out of? And then like does this have components of CI CD built into this? So these are the things that I think are maybe best practices from the software engineering slash DevOps world that are kind of slowly transitioning over to the machine learning side. And that's going to be an increasingly rare skill set. So we do filter for that as well as we look to hire data scientists these days. Again to summarize a high performing data scientist for us, good problem solving skills, good collaboration and communication, good foundational skills, especially as it pertains to statistics and machine learning class engineering component to their skill set. At least the aptitude to pick it up is what we look for. Now I know you had a question before this Today you see, right, like this is the age of the great resignation. So obviously there is a lot of talent mobility. Just the biggest challenge I see is just a career pathway for data scientists, right? Like where they can feel like they are being productive, they have autonomy and they have a sense of community. I think creating that environment is the biggest challenge. Not a lot of companies do this natively and at mark we're trying to solve this by just creating a separate role just for data science community leaders, you know, where they will be in charge of Creating, let's say, upskilling pathways and talent growth pathways and a sense of community where they said they can learn and grow. But again, it's an experiment that we have in progress and it is a challenge to retain like high performers just because it's a relatively new field, especially in places like health care. So just creating that career mobility and growth pathways is an ongoing challenge.
That's awesome and I thank you so much for this really holistic answer and harping on the OP skills for a data scientist. Do you think that in the future a standard data scientist will need to have the OPS skills or do you think that a new role will emerge? Machine learning engineer. Machine learning OPS engineer. Where do you see the data science role being general to a certain extent, or do you see it specializing more and more over time?
I think again, it goes back to the industry. Right. So if we limit ourselves to the three kinds of industries, this answer is going to differ based on what industry you're talking about. If data science is a core component, you're basically a product and there needs to be a strong OPS component. Right. So I think in those kind of settings you will increasingly find that your data scientist profile closely resembles an ML engineering profile. And that's probably true for the second category of companies as well, which where data is not their core product or data science is not their core product. But they have to make decisions in real time because a lot of the decisions need to be integrated into their systems. I think it's the third profile of companies where it's a primarily a decision support tool where there will still be room for statisticians and data scientists who can inform, let's say, decision making without necessarily having to go into full OPS mode. But that set I think is going to get increasingly smaller with time. I'm just neglecting one large piece of kind of data scientists, which is people in research roles within organizations. Right. Like Google Labs or maybe Facebook Labs, where perhaps there is still room for folks that are not OPS heavy but fundamentally want to focus on theoretical algorithms. But again, those are what I would consider increasingly shrinking profiles.
That's really great. I'd love to pivot to also discuss your work leading data at Merck as a data and AI leader. What are some of the exciting use cases you've seen or worked on at Merck that really excited you as a data leader?
Yeah, so when I was not at Merck and when I was reading about Merck and considering it as a potential place of employment. Right. So there were some publicly available kind of use cases that I ran across that had me really excited. Right. So there was a lot of work done in continuous drug manufacturing. So we were basically revamping how we do manufacturing within our branches to facilitate, let's say, intelligent automation and continuous drug manufacturing. There's a lot of work that we were doing in our supply chain and logistics as well that involved data science and machine learning. So that was exciting too. And then in the commercial side there was a lot of work that we did in intelligent and effective engagement. Right. So how do you figure out what the right message and the right channel and the right content content and the right cadence is to engage your customers with so that they see the value and benefit of the life saving products that we generate? I think that's where a lot of machine learning and data science comes in because it is fundamentally an intractable problem if you try to do it by brute force. Right. So somehow you need to have this predictive and intelligent component to it. So I think these are some use cases that I was aware of even before I joined and as I have entered this space, there's a lot of interesting work happening in let's say natural language processing to look at, let's say the promotional content that we send out and the engagement that happens with that to understand what is it that is resonating in our messages and what is not resonating so effectively. Right. So that we can be more curated in our engagement efforts. So that's a huge area of focus for us. There are other areas around, let's say next gen and advanced predictive modeling and forecasting to understand like what are the implications of certain decisions that we make today, five years down the line. So those kind of interesting work is also happening in the commercial space, which I find extremely exciting.
That's really awesome. And you know, as a data leader, one of the challenges you mentioned is change management data culture. You're not only tasked with operationalizing data science use case that have an impact on the short term, but you're also focused on long term transformational projects like change change management, enabling data culture and even research and development to drive long term use cases. How do you balance between these different priorities and these initiatives and how do you allocate your team's time and resources as such?
It's a loaded question, Adil. So I think this balance between business as usual and innovation is something we continue to strive for. I'll share with you an interesting experiment that we're doing and keep on using the word experiment within our Org structure because we are constantly undergoing transformations. So we have strong leaders who believe in just being agile and adaptable. So there's a bunch of experiments that we have already in flight both from a ways of working and culture perspective. So that's why I keep on going back to the term experiment. So we today have this org structure where majority of our data scientists sit in a flex pool, right? And as a result they get to work on different kinds of projects. So they're not tied to one, one thing that they do like throughout the year they can work on, let's say one franchise or one business unit or one type of problem, right? So that helps maintain a good balance between innovation and execution. We do also have a dedicated kind of research and innovation function within my team and they focus exclusively on external partnerships, branding, innovation and best practices. Right. So they provide that extra bandwidth for innovation, if you will, that kind of permeates throughout the organization. And then within the larger like CDO organization we have, like I alluded to earlier, data science community champions, right? Like those are dedicated roles that we have who are constantly iterating on our culture through events and activities to create that sense of community. We do follow constructs like objectives and key results like okrs to keep and track our goals. And we have dedicated in a spot there for innovative things that we would like to innovate, killing things that we would like to do. And then there's this concept that I think Paul Graham from Y Combinator pioneered, which is maker time versus manager time. It's very easy as a data scientist to be in meetings all day because you're just a glue that connects everything. So everybody would want a data scientist in their meeting and that we call let's say loosely, manager time. So how do you kind of find the right balance between like heads down problem solving mode, which is maker time versus let's say more managing people or managing stakeholders time. And loosely we try to strive for maybe a 60, 40 where 60% of our time we spend on problem solving and 40 we spend on let's say so the quote unquote managerial stuff as a group. So obviously this looks different from individual to individual, but like this loose kind of compass that we drive towards. So these are some kind of guardrails that we have that help us point in the right direction.
That's really great. I love this analogy from Paul Graham. I think that's a really great way to think about it. Now we mentioned as well data culture here and change management, how do you view the importance and the challenge of data culture when enabling the adoption of the solutions you create. And what have been some of the ways you've been able to move the needle on data culture?
Well, data culture is huge, right? So I mean, this is what I refer to as change management, because there's two kinds of culture, right? Culture that is for data scientists. So that obviously needs to be there so that we can be happy, productive, and we can retain them. And the major components there for effective data culture is autonomy, like a sense of autonomy on their work, a sense of community. Right. So that they feel like they're part of something larger and then just a sense of growth. Right. So they feel like they are learning either from a technical side or from a domain side and improving consistently. So I think those are three key pillars we anchor around. But there's a whole different side of data culture, which is data culture in the organization. Right. So data driven mindset, this is commonly referred to as. And unless we are asking the right questions, we will never be working on the right problems. Right. So to solve this, at Merck, what we have is basically an analytics translator role. You know, so within the larger organization, which is the CDO organization, we have dedicated data professionals. The right way to think about them is maybe they have a major in data science and a minor in business. Right. So they will sit very closely with our business stakeholders and they act as thought partners. So every time there is a question, there's a certain process that they follow. Right. For instance, what is the action that this question is going to drive? Right? Let's say the answer is 100 or let's say the answer is 0. Like how does your decision making change? Is this like an ad hoc thing or is there a larger problem that you're trying to get to which has more of a predictive or a product type component to it? So just kind of having that level of dialogue over time I think is going to generate maybe more advanced data driven thinking and a change in data culture. So again, another experiment that we have in progress, but we take this aspect of culture very seriously.
Yeah, that's really great and I completely agree with you. I think having someone in the room that can speak both languages, the business language and the data science language will elevate everyone's skill set, whether that's the, the business folks getting more of a data language or the data folks getting more of a commercial acumen. Now, Suman, as we close out, I'd love to look into the future and see what you think are the data trends and innovations that you're particularly looking forward to seeing within the pharmaceutical and healthcare space in the next few years.
Yeah, yeah. So maybe I'll limit it to three things because I am looking forward to a lot of things. Like everybody else, I'm looking to see how Alphafold and the major announcement last year is going to accelerate drug discovery. Right. So that I'll be watching very closely. Second, I think there's a lot of work that's being done on NLP and conversational AI outside of healthcare. Right. And I'm looking very closely to see how that translates into the pharmaceutical industry because we could definitely use some advanced kind of methods, unstructured data that we deal with on a regular basis. And then third is a little bit out there, but it's a space I'm watching very closely around let's say web3 and blockchains and how it is going to affect marketing. Right. Especially this concept of let's say privacy. First, first party data where end users have control over their data and there's no kind of middleman in the between. So there's no Google or Facebook that is kind of trying to track you. And like companies like let's say Merck will have direct access to your data with your consent and you get to monetize out of it will change the commercial landscape. Fundamental. Right. Because today the data we have is reliant on what let's say data aggregators provide us. Tomorrow is going to be all first party data or data that like you provide to us directly. And this concept of linking across multiple, let's say of your web experiences is going to be easy because of that's just one ID that you have throughout your Web3 experience. So I mean very early days for Web3, obviously it's still kind of in the ideation phase in many ways, but it's space I'm watching very closely because that's going to have huge implications on how we do sales and marketing and analytics around it in the future.
That's really awesome and really exciting. Now, Suman, as we close out, do you have any final call to action for today's listeners?
First of all, stay safe. I know it doesn't feel like Covid is still around, but it very much is. So continue following guidelines. Second, I would just say follow the life sciences data science space very closely because majority of the disruptions are going to happen in this space very soon. And then third, I will say we're hiring. So if you guys are looking for opportunities, please feel free to reach out that's awesome.
Thank you so much, so much for coming on the podcast.
Of course. Thank you for having me. I had a great time.
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