Dr. Jeffrey Gladden discusses thymic peptides like thymosin alpha-1 and thymosin β4, which can restore immune function lost with age. Thymosin alpha-1 has double-blind human trials backing it and is prescribed across Asia for cancer and viral infections. As the thymus declines, autoimmune disease rises in older adults, but peptide replacement works like hormone therapy for menopause.
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That's what thymosin alpha 1, which if we, again, people always say, well, peptides have no, they have no double-blind placebo-controlled studies. Thymosin alpha 1 does, has numerous human studies on it. It's a drug in other countries known as Zidaxin. So it's widely used in Asia and India for people with cancer, for people who have immune dysregulation, for people who are viruses. So it's a well-tested peptide. It's also an essential peptide to tell our immune system, oh, attack this, don't attack this, right? So it's a really critical player in immune function. And one of the reasons we get more autoimmune disease as we age is because of this lack of thymic function. At this stage, I'm sure, you know, you've read about people trying to do thymic regeneration or trying to do thymic, thymus replacements. At this stage, the best that we really have is to replace what the thymus gland does. And that's the thymic peptides, thymus alpha 1 and thymus beta 4. So those two peptides are gonna now kind of replace the fact that I don't have a thymus gland anymore. Just like my ovaries aren't working well anymore, neither is my thymus gland. So why wouldn't we think about replacing those in the same way?