Dr. Jeffrey GladdenFounder & CEO of Gladden Longevity

Can We Reverse Aging? The Longevity Breakthroughs to Watch

15 Oct 2026 · 1 min

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1:14

In this brief dialogue, Speaker A emphasizes that aging should be approached as a systems problem, where numerous molecular and cellular damage processes interact and influence each other's accumulation. Given the limited tools currently available to delay late‑life health issues, the speakers argue that interventions must be personalized to the individual. They note that anti‑aging or longevity medicine is fundamentally preventative, aiming to treat people before disease manifests, with the primary goal of extending healthspan and the secondary benefit of potentially increasing lifespan.

Um, uh, I fully agree that this is a systems thing, that, um, the only way we can make progress here is by acknowledging that the body consists of a vast number of processes that are, um, interlocking, that talk to each other.
That's right.
That aging is no different, that the various types of accumulation of damage in the body at the molecular and cellular level influence the rate of accumulation of each other. So the right way to go about this, especially these days when we only have rather limited tools to postpone the health problems of late life, is to optimize those tools for the, for the individual. And of course, you and other knowledgeable physicians in this space have been very careful to emphasize how important it is to do that personalization. This is especially true, I would say, because of course, anti-aging medicine or longevity medicine or whatever we like to call it is overwhelmingly preventative. We are seeking to treat people who are not yet sick, and who we don't know how soon it's going to be before they get sick. But we do things to increase that period, to increase healthspan, and of course, to increase lifespan as a kind of side effect of increasing healthspan.
That's right.