Dr. Jeffrey GladdenFounder & CEO of Gladden Longevity

Hidden Insulin Resistance‼️#longevity #insulinresistance #shorts

10 Sept 2026 · 1 min

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In this short video, Dr. Jeffrey Gladden explains that his clinic performs a 2‑hour oral glucose tolerance test (OGTT) on every patient. He points out that many individuals who appear metabolically healthy—showing a normal hemoglobin A1C (5.3%) and fasting glucose (89 mg/dL)—exhibit marked insulin resistance when challenged. During the OGTT, insulin spikes to around 60 µU/mL and remains elevated at about 80 µU/mL after two hours instead of returning to baseline. Dr. Gladden emphasizes that this “stress test” on the pancreas uncovers hidden dysfunction, allowing patients to better understand and manage their metabolic health.

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I'll tell you this, we do 2-hour glucose tolerance tests on everybody that comes into the clinic, and it's stunning to see how many people have insulin resistance that don't know they have it. Hemoglobin A1C 5.3, fasting blood sugar 89. You do a stress test on the pancreas and the next thing you know, boom, right? The insulin goes up to 60, and at 2 hours, instead of coming back down, it's now at 80. It's really phenomenal to see, to look behind the curtain, so to speak, and actually see what's going on. And it helps us, I think, help people understand how to manage what's going on.