Integrating Mental Health in Chronic Disease Management - Episode 303

25 Sept 2025 · 33 min
Episode

25 Sept 2025 · 33 min

0:00

Podcast interview (Gladden Longevity Podcast, Ep.303) with Dr. John Oberg about a clinical program (Prisina/START) that integrates mental health, behavioral micro-changes, and rapid medication titration to reverse chronic metabolic diseases. Early study: 50 low-income patients averaged A1C 9.6 → 6.4 in 12 weeks; 83% retained control two years. Larger second cohort averaged A1C 11.06 → 7.8 in 12 weeks; 7.2 at 24 weeks; 30% off insulin. The approach emphasizes small, patient-specific steps (example: changing ice cream choice lowered fasting glucose by ~100 mg/dL in one week), pod-based teams, provider training/fellowship, AI-assisted scaling (13 AI use-cases), and employer/payer partnerships to scale and lower costs.

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