A short spoken explanation (by Dr. Tabatha Barber) about how autoimmune conditions—specifically Hashimoto's thyroiditis—cause the immune system to attack thyroid tissue, reducing production of T4 hormone. The excerpt explains the resulting hypothyroid picture and the compensatory rise in TSH as the brain signals the underactive thyroid.
Another one is autoimmune conditions. Like, I have Hashimoto's, which means my thigh, my immune system attacks my own thyroid tissue. And when it does that, it prevents my thyroid from being able to make enough T4 hormone. So what happens is then you start to look like a hypothyroid patient because you're not making enough T4 hormone. And initially, if your T4 is low, then your TSH level will increase, it will go up because your brain is sensing that the thyroid is not doing its job, and so it starts yelling at the thyroid with more and more hormones.
