Short YouTube transcript from Dr. Tabatha Barber explaining that progesterone receptors exist throughout the body (breasts, cardiovascular system, brain, bones, skin) and that unopposed estrogen in tissues can cause symptoms (anxiety, poor sleep, weight fluctuation, bloating). The speaker concludes that people on estrogen replacement likely should also take progesterone.
We have learned that there are not only progesterone receptors in the uterus, but all throughout our body. There are progesterone receptors in our breasts, in our cardiovascular system, in our brain, in our bones, in our skin, like everywhere. So if you have unopposed estrogen in other parts of your body, like your brain, it doesn't feel so hot. And you'll notice because you probably have more anxiety, you're probably not sleeping as well, your weight may fluctuate, and you're puffy or bloated and swollen. You probably should be on progesterone if you are an estrogen replacement.
