The Safest Type of Estrogen (HRT) You Should Take
19 Dec 2023 · 0 min
0:22
YouTube video by Dr. Tabatha Barber (uploaded Dec 19, 2023) discussing hormone replacement therapy choices. The speaker contrasts bioidentical estradiol delivered transdermally (cream, pellet, patch) with oral conjugated equine estrogen tablets, noting transdermal routes avoid the hepatic/gut "first-pass" effect and thus are not converted into estrone the way oral conjugated equine estrogens are.
Questions this video answers
Topical/transdermal routes: cream, pellet, patch.
They undergo first-pass metabolism and are converted into estrone.
