Does Oprah Have The "Obesity Gene" 🧬

18 Jan 2026 · 1 min

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1:13

In this short monologue, Eric Roberts addresses the recent claim by Oprah that she possesses an "obesity gene" and uses it as a springboard to discuss the science behind genetics and weight management. He clarifies that there is no single "obesity gene" that determines a person's ability to lose weight, but genetic factors can influence metabolism, energy expenditure, and hunger hormones, making weight loss easier for some and harder for others. Roberts shares a personal example of his naturally high energy and fidgeting, which burns extra calories, and explains how variations in appetite-regulating hormones can affect satiety and eating behavior. He emphasizes the well‑known principle that genetics may load the gun, but individual actions pull the trigger, underscoring that weight loss ultimately depends on calories consumed versus calories burned. The video concludes with a call‑to‑action directing viewers to a link in his bio for personalized calorie guidance.

Chapters

Oprah recently said she has the obesity gene and that's why she eats too much, and she's getting grilled in the comments. So is there such thing as an obesity gene, and is it stopping you from losing weight? Well, no, there's not an obesity gene, but do genetics make it easier or harder to lose weight? Absolutely, and here's how. I'm someone who's very naturally high energy. I'm always tapping my foot, talking with my hands, moving around. This means I burn more calories and have a higher metabolism than most people, making it easier for me to lose weight. Or someone might have different levels of hunger hormones. So if you have less of the hormone that tells your body, I'm full and satisfied, it would be harder for you to lose weight because you would keep eating. But the saying goes, genetics loads the gun, but your actions pull the trigger. Even if you have shit genetics, you still decide what you eat and how much you move. And weight loss will always come down calories in and calories out. And if you need to know how many calories you should be eating, click this link in my bio.