Defining Histamine Intolerance and Mast Cell Activation Syndrome

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Hello, friend. What do you know about histamine intolerance? Defining histamine intolerance in this episode, along with lesser-known mast cell activation syndrome, could help you stop struggling with headaches, migraines, other pesky little nuisances and get answers to an undetermined source of problems. If not for you, someone you know or work with, or one of your health pros who's drifted over from the She Means Fitness Business podcast. Okay, my guest has something special. Beyond that, she has something even more special, so I want you to stay stay tuned even if mast cell activation syndrome or histamine is something new to you, because the signs and symptoms of histamine intolerance are so very related to other signs of gut dysbiosis— meaning, you know, the gas, the bloating— that if you feel like I'm doing everything right I followed the instructions and it is still not helping. You actually may be in fact feeling worse. Some of you have said these very words to me or written them, and it's because you may be feeding the very thing that's wrong. So let's put a stop to that right now and/or arm you as a health influencer, you midlife woman, you so that you can prevent it for yourself or for someone else. My guest is Dr. Meg Mill. She's been on the show before talking about headaches and migraines. She's here as a pharmacologist and certified functional medicine practitioner with over two decades of clinical experience. She's also a bestselling author, podcast host, summit host, and sought-after corporate wellness speaker. Her virtual functional medicine practice has transformed the lives of hundreds of clients worldwide by connecting the dots between their diverse, unexplained, and often overlooked health struggles, such as— are you sitting down— gut issues, chronic fatigue, migraines, skin reactions, anxiety, or allergies. She uses her E.A.T. method to uncover and resolve the underlying connections, whether it's gut dysfunction, hormone imbalances, histamine intolerance, or MCAS. She empowers clients to take control of their health so she can regain the energy, mental clarity, and confidence needed to fully show up for your life again. She's been seen in national publications and on media such as Fox News, She's ABC, NBC, CBS, CNN experienced for Reader's Digest Health Magazine, Mind Body Green, Authority Magazine, Life and Style, and Sunset Magazine, as well as several national publications, blogs, and podcasts guest appearances.

As we dive into this, it's a lot of science, but hold on to it.

Some of you will love that. And for those of you who don't focus on the symptoms, that this may help.

I'm Debra Atkinson. You're listening to Flipping 50. I started this podcast over a decade ago to answer questions about fitness in menopause and beyond before you knew to ask them. The goal: to help accelerate your results with science and the practical application of proven protocols while living your best life. There's no more powerful health influencer in the world than a midlife woman, and it's not just about you, but the 3 generations that you influence. My unique 40-year career, including being a university senior lecturer in kinesiology, an industry subject matter expert, and an international speaker, to founder of the first and the only exclusively made-for-menopause-and-beyond fitness membership in the world. Every week I interview experts behind the scenes and the science of optimal hormone balancing, fitness, and longevity, and share answers to our community's questions so you can have the vitality and the energy that you want, need, and deserve.

Dr. Meg Mill, thank you so much for being here.

Thank you so much for having me.

All right, this is going to be, I think, a gold mine for many of our listeners, even though they don't know what And I think this is always where some of the jackpot and the gold in podcast is, is that we know this is Flipping 50, this is for you. You generally come because you're seeking exercise or fitness or health and wellness advice at the very least. And not all the topics of every single episode would you have said, oh, I wanna look for this, but it ends up being, something you didn't know you needed to know, and I hope this is how it hits you. Let's start at the very beginning by what is histamine? How does it affect us and impact us?

Yes, absolutely. And I think it's— this is going to be really an interesting and a different topic because it's something that affects a lot of people and we don't know it, and it affects us in a lot of ways. And there it might be like the aha, this is connecting some of the dots for me of all of these different symptoms. That I didn't know I have, because we're looking at it a little bit differently and we'll get into how it can affect all different areas of your body. So let's just start by talking about really what is histamine. So histamines are compounds and they're made by our white blood cells, our mast cells and our basophils. So you want to think of this as part of your immune system. So I'm going to just take a little bit step back and say we have an innate immune system and adaptive immune system. So our innate immune system is really the guards. They're on alert, they're ready to go, and they are looking for pathogens. And the mast cells are part of our innate immune system. So when we have a pathogen that comes into our body, these mast cells are going to degranulate and they're going to shoot out several different chemicals, one of which is histamine. And so your histamine has a lot of purpose. It's actually meant to protect you. But what starts to happen, and we'll get into, is some things get off balance and you start to get symptoms of histamine intolerance. So I think of histamine sort of the way I think of cortisol, and they get a bad rap. So, you know, no one— everyone's talking about like, oh, cortisol, you know, high cortisol or histamine intolerance, and they can become off balance. So we start to get these symptoms, you get a bad rap, but they actually have purpose. So, you know, some of— let's just start with some of the purposes where histamine is an immune mediator. It helps the body protect against pathogens. It actually helps your body create inflammation. And while inflammation unregulated is a bad thing, it actually is a good thing when we're trying to fight something and heal from an immediate threat. It also— histamine can also stimulate production of gastric acid in the stomach, and so it can help with digestion and absorption. It acts as a neurotransmitter, so it actually affects your wakefulness and your sleep cycles. It can help in wound healing, in vasodilation, in order to get the blood flow so the immune system can get to the areas that it needs to repair. You can see it in an allergic response, so it's protecting you if you have an allergic response. Even in bronchoconstriction, because, you know, you're going to think of histamine as maybe an asthma or something like that, but there's purpose in the bronchoconstriction because it's preventing harmful pathogens from even getting into your lungs. So there is that purpose of it. It just becomes a problem when it gets out of control.

Got it. Such a great description. And I think what comes to mind for most people when you hear the word histamine, it's like, oh, allergy season.

And that's where most people are associating histamine. So we definitely will see that in allergies because like we're saying, you're body's protecting you from an allergen, but we're also going to see other symptoms because we actually have 4 different type of histamine receptors. So you're actually having histamine receptors in your brain, in your gut. So interestingly enough, you may have gas and bloating as a sign of histamine intolerance. That's one of the biggest signs of histamine intolerance, which you're not really expecting it to be a histamine issue.

Exactly. So glad you brought that up. So for you, when you are identifying it or recognizing it where somebody else hasn't, because often, you know, right now everybody's talking gut health, it's almost trending, right? I mean, it's like, oh, you have gas and bloating, it's probably you need probiotics, you need digestive enzymes. How long could a woman potentially be dealing with a histamine issue typically and be trying all of these other things but just prolonging the problem? Do you see that frequently happening?

I do. And this is where it gets very confusing because one of the things that you have to do in order to actually help histamine intolerance is heal the gut. However, a lot of the mainstream things that we're talking about— so if, you know, you're what, you're flipping through social media, you're going to see probiotics and fermented foods often recommended, and those are really important for gut healing, but they're actually going to aggravate histamine intolerance. So you have to make sure when you're dealing with histamine issues that you're doing it in the right way, in the right order, or sometimes you could actually be doing the things that you're thinking are helping your gut and you're actually stimulating responses and you're creating symptoms. So I'm going to— I'll just go into a little bit about kind of why it starts to happen. So you want to think of your body like a bucket with holes in the bottom. So you have this bucket and you're constantly filling up the bucket with things that can contain histamine. So maybe you're, you know, exposed to some allergens or maybe you have some gut health issues or maybe you are eating high histamine foods or we have, you know, we have these things that are filling the bucket, but we also have holes in the bottom of the bucket, and those are enzymes that are breaking down histamine. So as long as your enzymes are working and they're breaking down histamine, then your bucket's filling, you're draining, your bucket's filling, you're draining. And where we start to see the symptoms, and we can get into the symptoms, are when we start to see this overflow in the bucket. So when, you know, we either see too many things filling the bucket or the holes start to get plugged and we start to see that we can't drain the bucket. So what we are— what breaks down histamine in our body are two different enzymes. The first enzyme is diamine oxidase, and that we call the DAO enzyme, and that actually lives in the brush border of your gut. So that's where you're going to be breaking down the foods that you— that contain histamine. So, you know, we may be eating histamine foods and just breaking them down, we're fine, but that can— once we start to get some intestinal bacterial overgrowth, we start to get— that enzyme starts to get compromised. So once, you know, we can see the enzyme getting compromised, and then we're not able to break down the histamine as well. So we have— that's probably the leading cause of the DAO enzyme, um, not really functioning as well. So we need to do gut healing, and that's a primary thing. Then we can also— some people have genetic factors, that affect the production and functionality of that enzyme. So you can just be genetically predisposed to not breaking down histamine well. Now, when we actually do the gut healing, I generally see people that you can usually tolerate histamine to an extent. So it's usually not— the genetic factors aren't strong enough that when we're setting you up for success with all of the other factors, we can't compensate for that. But there's— it's almost like filling— that's another thing that's filling that bucket. We also need— we know we need certain nutrients to actually create the enzymes. So we need things like vitamin B6, copper, zinc, vitamin D for optimal enzyme deficiency. And it can become complicated because when you have an underlying dysbiosis going on in your, you know, intestinal tract, you might not be digesting and absorbing the nutrients that you need, even if you're eating the most healthy foods. If you're not digesting and absorbing those nutrients, then you may not be getting the nutrients you need to have the enzymatic activity that we need to. So we get some of these feedback loops. Another thing that we can see are certain medications like NSAIDs, some antidepressants, some immune modulators. They can interfere with that enzyme activity. And then we actually— and we can get more into this— hormonal fluctuations. So progesterone can help the enzyme activity and estrogen can decrease it. So sometimes when we get hormonal imbalances, we see that start to happen. So, you know, those are getting the plugs. We have another enzyme called histamine N-methyltransferase that also breaks histamine down within our cells. So that's another enzyme that can become compromised. And we see, you know, some genetic factors. The polymorphisms can affect the expression of the HNMT. We also sometimes methylate— a lot of people have methylation issues. You need SAMe as a methyl donor. So if we have like low, again, B6, B12, folate issues, methylating, we can have issues there. We can also— liver function is important. Good liver function is important. So if we start to get compromised liver function, if we have excessive alcohol consumption, excessive toxic exposure, those can all affect that HNMT enzyme too. So those are the ways that it's sort of getting clogged., and you can't break the histamine down like someone else would. You're not born with histamine intolerance. Usually it's something that develops from some of these imbalances.

So question, I'm only imagining, but tell me if I'm valid in guessing this, but that a woman may get to a very frustrated level before she ever realizes or pinpoints that it is histamine. Is there an easier or faster way to distinguish, is it that or is it something else?

You know, I— that is hard because so it's affecting all of your systems because as we're saying that there's in most of our cell, you know, we have this in most of the cells in our body and we have, you know, the 4 different types of histamine receptors. So it's kind of when I see people, I'm looking at a collection of symptoms. So let's talk a little bit. You can see the nasal congestion, you know, sneezing. You could see asthma. You could have headaches and migraines. You can have fatigue. You can have heart palpitations, dizziness, anxiety, difficulty concentrating. You can have irregular periods or PMS, flushing, joint pain, sleep disturbances, high or low blood pressure. You get hives, vertigo. So like when you're seeing all this, it's, it's this wide variety of symptoms. So one of the things you can think— and the thing is you might not have all of them, and that's where that makes it confusing because you can have some of them, not all of them, and it, and it is a little bit hard to detect. So when I see people though maybe that are having, you know, headaches, getting regular headaches, and they have nasal congestion and they're tired, or maybe they're anxious and have bloating and gas and have— and so you're kind of looking at a combination of symptoms. Another thing you can just try to do, which this isn't the long-term solution, but it is a good investigative piece is try a low histamine diet. And it's one of those things that I don't necessarily recommend long-term, because long-term we really need to get to the root of why you're having the histamine intolerance. But we want to use it for investigation in order to see, okay, you know what, if I'm pulling histamine foods out, if, you know, does that make me feel better? Because we're bringing that load down. So when we're doing the low histamine diet, we're looking at different kinds of foods. So we're looking at foods that are high in histamine. So think of, like I was mentioning, the fermented foods, the moldy cheeses, vinegar, bone broth, avocado can even be. So some of these are healthy foods, which makes it confusing. And it's a hard diet. And that's why I always tell people, you know, sometimes people come to me, you know, we're getting savvy. I love how savvy everyone is getting about their health, you know, listening to podcasts like yours and getting all this information. And sometimes, you know, I— people will come and say, okay, I've been on this low histamine diet for a long time. I always say this is really more for investigation because there are nutritious foods on here, and it— and not everybody's going to respond to everything, but we need to just investigate. Does it— does it make a difference for you? So when you're pulling out some of these foods, do you feel better? Or if you're putting them back in, do you notice Okay, my nose, you know, these are little things that you may not be thinking about when you're eating. So like, if you're eating something, does your nose run after your dinner? You know, you may just think, oh, I'm— my nose is dripping, and I— you're not paying attention to what did I actually just eat that could be causing that? Does your face flush? It's a vasodilator. So are you getting red at different times? Are you seeing flushing? So those are some like little tricks to say, how do I feel after some of these high histamine foods. And, you know, these are really more to lower that load while we're figuring out how to resolve it.

Got it.

Okay, so question about— you mentioned some of the other signs and symptoms that somebody might not even associate, but what about headaches and migraines? So you mentioned, is that more chronic or is that also directly related, like within a few hours or the day of having higher histamine foods, you're going to notice headaches if you're having them?

So I actually see that very commonly in the women I work with, headaches and migraines. I see histamine issues as a really strong connector. So monitor yourself, and this is how— where it can be confusing— for the next 48 hours. I like to, when I'm working with people with headaches and migraines, I actually like them when they get the, like, the migraine, let's say, to make a list of what they've eaten in the last 48 hours. And I can't tell you how many times people have found the connections. I mean, we've seen olives, we've seen citrus fruits, we've seen like peanuts. There's just so many things. And you also want to think a little bit about the, the load, about the threshold, like how much of it you ate. Because if you're eating more of it, you might have more symptoms. But once you start to really look and investigate, you can start to see some of these patterns. And then people are enlightened, and it's like this amazing thing of enlightening of, I can't even believe that this was triggering me and I never realized that for all of these years.

Hey, this is Debra Atkinson, and there is one thing you can't do in the gym at your age, and that's get all the protein that you need. You've got to do that in the kitchen. To make it easy for myself, not only to get the protein but the fiber, the fruits and vegetables I want daily, I started started drinking a smoothie a day 30 years ago. But when I realized all the junk, the sugar, and the extras that you don't want, that I don't want, hiding in most protein powders, that's when I finally caved in after years of saying I will never ever ever sell supplements. Stop skipping, skimping, and sabotaging yourself in the morning after workouts by always being prepared. Look, yep, I agree, real food first, but it's just not convenient to carry a turkey sandwich. Sometimes the protein— and don't forget the fiber— they kill cravings and they boost satiety.

And you've got to make it easy to do the right thing.

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Wow. Yeah, right. And feeling like you've lost time, or, you know, you donated it somewhere and you can't ever go back and get that. Oh, and okay, so you pointed to the link to progesterone and estrogen and the changes there. Does that mean that maybe a higher percentage of people you see with histamine issues than are midlife women?

It can be more common in midlife women, and that's because— so when we're starting to go through perimenopause, we start to have a decrease in progesterone before we have a decrease in estrogen. So a lot of women in this time of life are estrogen, you know, become estrogen dominant through this life, this time of life. And so there's a couple different dynamics. So first, first of all, we'll talk— let's talk about estrogen. So estrogen can make mast cells more reactive because mast cells actually have estrogen receptors on their surface. So when estrogen binds to the receptors, it can actually trigger a release of more histamine. Therefore, higher levels of estrogen lead to higher levels of histamine release. From the cells. And then histamine can influence the hypothalamus. It's a key brain region that regulates our hormones, and it can stimulate the hypothalamus to release our gonadotropin-releasing hormone, which can stimulate the pituitary gland— we're all connected here— to secrete LH and FSH. So in response to this increase in LH and FSH, the ovaries release more estrogen. So you get this positive feedback loop for more histamine can lead to increased estrogen production, which can exacerbate symptoms and lead to more histamine. So we need to really unpack that and really look at that, that really that cycle. And then we're also seeing it, estrogen can also in addition inhibit the reactivity of the diamine oxidase enzymes that breaks down the histamine that we're talking about. So we see that in two different areas. And then in addition to it, progesterone is believed to help stabilize mast cells and help the DAO enzyme, the DAO enzyme, actually work. So when we start to get that estrogen dominance and, and the decreased progesterone, we can start to see these histamine issues appear. And so that's why sometimes maybe weren't having histamine issues before and now they're starting, and you're like, okay, now I do have headaches and I never really dealt with that, or I'm always congested, or I'm bloated and I'm fatigued. And some of these things start to present as we're in that hormone balance. So hormonal balance is another thing that you can do to help with the histamines.

Great biology lesson.

It is, and yet I think we need it. You drew a great circle, and I think I'm I'm trying to follow along with my imagination of how that actually looks like.

And it's—

I, I think it is so frustrating because I think what one thing we're talking about, just to break this down in a way like we normally do, is it's the symptom, like, is not necessarily pointing you to the problem. Like the headache, the migraine, you know, I think we're not gonna default to think, oh, That's probably histamine.

Nobody does that.

And I think that's where it gets complicated. Again, once again, to be a woman, here we are. But I love that there's now an answer and there's more people talking about it. And I think we could all probably benefit, especially when not just women in midlife, but I feel like using our tagline, you know, there's no more powerful health influencer in the world than a midlife woman. So for all of the young women that you can also help as they come into this, you know, in helping identify with those others that are in your life, how does this all— now you've tied it in earlier to this being a part of it, but mast cell issues, I mean, how is that related? And yet also, is it different and distinct in its own?

Absolutely. So mast cell activation syndrome. So we'll go back to those mast cells so that we know that mast cells release the histamine. And what happens in mast cell activation syndrome, that's one of the things. So remember back in the beginning when I was talking about filling the bucket, that's one of the things that fills the bucket. So what can happen with mast cell activation syndrome is that we start to get overactive, hyper-responsive mast cells. So when I was talking originally about how your mast cells release the histamine when you have the, the pathogen or the threat, we start to have problems where these mast cells are releasing histamine for inappr— and other, and other mediators for reasons that are inappropriate. And so we're just seeing this hyperactivity, hyper-responsiveness of the mast cell which is causing all of these symptoms to occur. So mast cell, it's a little bit confusing because the symptoms can overlap, so you need— but they're different. So, you know, mast cells can cause histamine-type symptoms because histamine is one of the mediators released, but it can also have, you know, other symptoms too, and it can cause histamine intolerance. But you can So you can have histamine intolerance without mast cell activation syndrome, and you can have mast cell activation syndrome without histamine issues. But generally, people that have mast cell activation generally do have histamine issues. And so when we're looking at mast cell activation, we need to look at really why are these mast cells becoming activated. So when you go to your doctor and, you know, you're having histamine issues or mast cell issues, a lot of times they're going to put you on an antihistamine. So that's going to be the, you know, when we're— when we think of it, we think of the allergies, the antihistamine. And again, we're just band— I feel like it's so many Band-Aids, but we're Band-Aiding it. So we can Band-Aid it with antihistamines. You can Band-Aid it with, you know, I would say more use more natural things like quercetin, vitamin C, and those things. Those are also going to help you know, regulate the immune system and maybe decrease some of your symptoms. But the key really is to finding the root cause, or I say more causes of the symptoms. So what, you know, we're talking about most likely for the histamine intolerance, we have underlying gut issues because we see a lot of those compromised enzymes causing the problem. For mast cell activation, that can— there's something stimulating your immune system to become hyperresponsive. And we, we can see gut health issues there too. So we can see parasites, we can see foreign invaders, we can see Candida, we can see bacterial infections coming from underlying gut issues. Then we often will also see things like mold, mycotoxin illness, we'll see Lyme disease, we'll see heavy metals, we'll see environmental chemicals, you know. So we're really looking at what are all of those things that are causing your immune system to basically go haywire.

So there's so much to consider.

It's complicated.

So where is it that you begin? So when you talk a gut, is that a stool test or something else?

Yeah, so I do a stool test, and that is because we actually didn't even get into this grade of detail. So another thing that can actually happen is that we can get microbes in our gut that actually are histamine-producing. And so there, you know, this is— I'm just going to give this story, and it's actually a man that I'm going to tell a story about, but it was such a distinct story that he was like blown away. And that's why I want to share that connection. So I was working with someone years ago who actually came in to me that he was— had so much itching on his skin that he had to take a really strong medication that makes you drowsy all the time. And as soon as the medication wore off, he would just be like complete body itching. So he'd been having this for 20 years and he could remember the exact day that he— that it started. So for 20 years, he's— and he just never thought that it would go away. But he's going to the dermatologist. They keep putting on more and more medications. They're giving him shots. Nothing's working. And so he said, you know, we're going through his health history and I was like, we need to run a stool test. And he's like, well, I'm not having any gut health issues. Like, I'm, I'm, you know, I never have issues. I never feel bloated. I never feel uncomfortable. I'm, you know, having bowel movements. And I said, you know, I think there's a histamine issue and we need to check and see. And here he had histamine-producing, an abundance of histamine-producing bacteria. And we just had to— within 3 weeks, he had no itching. And it's like, wow, just this dramatic—

these—

so you can see these dramatic life changes when you're living with something for years and years and years, and there, there was just such a simple solution and just no one ever checked it.

Wow.

But happy ending.

So happy ending. And yeah, and so then we look at that, we have the stool test, we can, you know, find these imbalances, we can build up the good bacteria, we can you know, killed off the histamine-producing. But again, just make sure if you suspect that you have histamine issues that you're actually going to someone for gut health that understands histamine and can respect that and treat you in the right way, because some of the things that may be recommended could actually exacerbate your issues.

Yeah, such a good distinction. And I think it's just so good to unpack this, even if you feel—

and this is the the usual way that it feels.

I mean, Meg, do you agree with this? I mean, the first time something is revealed to you, it's new enough that it's almost more confusing and you feel like, oh no, I wish I could shut the door and not, and unsee what I just saw. Because you know enough to be dangerous and maybe don't completely understand it. But I think this is where actually I'm gonna dig a little bit because I know that you have an upcoming summit you're hosting really to dive into this and tell me what the, the biggest opportunity you think is with this summit. Is it helping people to understand it and number one, understand that there is help in getting over it?

Exactly. So we're going to have over 50 experts on the summit in this area, and I think just really getting the word out and understanding, like you're saying, not a lot of people understand that this even occurs, that this could be what they're experiencing. You know, we have so many people that are saying, and you may feel like you're one of these people, I was one of these people a long time ago, that go to their doctor and they're just told, oh, you're fine. And I had someone last week tell me, I know I'm not fine. I know what fine feels like. And that's not what I'm feeling. And I was like, the purpose said perfectly, because you know that there's something off and that you're not feeling fine, but you're being told that you feel fine. And this can be a connection for a lot of different symptoms, and not a lot of people are understanding or aware of it. Mast cell activation syndrome wasn't even a diagnosis until 2016. We're seeing it dramatically increase after the pandemic. So when we're— look, you know, because it's an immune system issue in that part. Like I said, you can have histamine intolerance without having an immune issue, but when we're looking at the immune issue, we're seeing this increase and people aren't getting answers because like you said, we don't even know it's there. So, you know, we're really trying to get the word out that this could be the connection and really looking at this and considering it as a possibility when you're on your health journey because not a lot of people are understanding it.

So appreciate this. And I mean, you have me scratching my head honestly because I do get headaches, I do get migraines, and I know we've talked about this before, but But I think it's so good to look at underlying reasons like this and to reflect, okay, I know I need to keep a little bit better track of my food log and see what's going on with me. But will you tell listeners the dates of the summit and how they can get involved? Who else is talking? Just share a little bit, if you will, without giving it all away.

Yes, well, yeah, we have Debra's on it, so Debra's gonna tell— give us some good— make sure you listen to her talk. And we have, you know, we have 50 experts. We have Dr. Neal Nathan talking, you know, he's a leader. He— you may have heard about the book Toxic. We actually have Carrie Jones on as a hormone expert. So if you're, you're midlife and in that, you know, looking at your— having those perimenopause Symptoms. We're going to unpack like a full talk on the actual mechanisms. You can get a little more of that chemistry behind the biology lesson there. We have Cynthia Thurlow coming on talking about fasting. We have Jaben Moore. We have a whole bunch of experts that are going to give you great information. What I wanted to do with the summit is really give you information on what this issue is, but really how it connects to all different facets of your health, how it's affecting different areas of your life. Because Debra, you're saying, okay, you have the headaches, and so maybe that's where it's coming in for you, but maybe someone else is expressing it with fatigue. And so maybe someone else is having allergy issues. Maybe we're all— it's because we have these different receptors and it's affecting us different ways, we can see a lot of different issues. And so we're trying to bring that all together. We are— it is June 18th through the 24th. So, and it's a free event, so you can, you get it for free. You can go to my website, www.megmill.com. It's just M-E-G-M-I-L-L.com. Dr. Talks is the producing company for the summit, so you can even go to Dr. Talks and find out more information there. And, you know, I am on Instagram at Dr. Meg Mill. It's just D-R. Meg, M-E-G-M-I-L-L. So I'll be posting things also to give you links to join.

So good.

And I think this is so needed, even though it may— we may have just kind of hit you over the head with this first thing. It's like, oh no, there's another reason my gut could be going wrong. And yet for some of you, it will be such a relief because nothing that you have tried actually worked, and there's a different thing to explore. It's not you, and no, you don't have to tolerate it, nor should you. Put up with it because if we're not absorbing things that we should be from the healthy food and efforts we're making, we want to do something about that sooner rather than later. Dr. McMill, thanks so much for being here. Thank you so much for having me. Okay, everybody, so I know there was a lot to unpack here, and if there's a question that you wish I would have asked, I'm just going to guess and intuit that potentially you didn't know what to ask, and hopefully we asked enough so that you feel like you've got a better handle on what this is and who or how it might show up if you are impacted. So in the show notes, we will put the link to join the summit. I'll be sharing that on social too, so you'll see it probably all over. But show notes for today will be at flipping50.com/defining-histamine-intolerance. And what are you waiting for? Let's start flipping 50 today.

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