LIVE: State of the Early-Stage Venture Market with Chemistry Ventures Ethan Kurzweil + Jason Lemkin

10 Apr 2025 · 58 min
57:33

In this live YouTube discussion recorded on April 10, 2025, Jason Lemkin interviews Ethan Kurzweil, co‑founder of Chemistry Ventures and former Bessemer partner, to dissect the current early‑stage venture landscape. They begin with the origin story of Chemistry Ventures, emphasizing a return to pure early‑stage focus, alignment with founders, and a small, all‑in team. The conversation then shifts to macro trends: seed and Series‑A deal counts have fallen from the 2021 froth, average round sizes have risen, and the typical interval between seed and Series‑A has stretched from about one year to roughly two years. This creates a “crunch” for founders, who now often need multiple seed rounds and must plan for three years of runway. They explore the perceived AI premium, noting data that suggests a 20‑60% valuation uplift from seed through Series‑B for AI‑tagged companies, but caution that the premium is tied to real product‑market traction, not AI for AI’s sake. The duo outlines the key metrics investors scrutinize at Series‑A: net new ARR growth, net dollar retention, gross logo retention, CAC payback period, burn multiple, and ACV, stressing honest, nuanced reporting over vanity numbers. Storytelling is highlighted as a critical differentiator—founders must articulate a clear “why now” narrative, align product vision with market momentum, and avoid over‑reliance on slides. Fundraising process advice contrasts a “tight” rapid data‑room sprint with an “intentional” relationship‑focused diligence, arguing that founders should prioritize fit and depth over speed. They discuss the high growth bar required for profitable exits (e.g., 50% growth to a $500‑$1B IPO) and how that shapes seed‑to‑Series‑A expectations. Finally, they debate moats in the AI era, suggesting that traditional lock‑in is eroding and that developer/user love becomes the new moat, while also noting the impact of free, high‑quality AI tools on switching costs. The session wraps with practical calls to action for founders to reach out to Chemistry Ventures.

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