Muse Wonder, Social Reckoning Review, Apple HomeView | Eli Manning & Michael Waldron, Anjney Midha, William Chu & Negin Oliver, Neal Stephenson, Ravi Gupta & John Hegeman, Jack Goldburg, Oege de Moor, Nick Talken, Jeff Holden

13 Oct 2026 · 172 min
TBPN

13 Oct 2026 · 172 min

0:00

In this episode of the roundtable podcast, host John Hegeman and co‑host Jordi Hays guide a lively discussion with a rotating panel of guests spanning AI, chemistry, manufacturing, and entertainment. The show opens with a celebratory gong and the announcement of a $55 million Series B round led by TCV for Alberts, a startup building chemistry‑native AI. Nick Talken explains Alberts’ mission to replace paper notebooks with AI‑driven lab assistants, emphasizing the need for domain‑specific retrieval models that outperform general‑purpose models by 45× due to proprietary enterprise chemistry data. The conversation explores the long‑term strategy of fine‑tuning versus building bespoke models, the cultural impact on chemists, and the broader “holy grail” problems in materials science such as better ablative materials for spaceflight, longer‑lasting batteries, PFAS remediation, and medical microrobotics. The focus then shifts to Jeff Holden of Atomic Machines, fresh out of stealth with a $250 million raise. Holden describes the “Matter Compiler,” a combinatorial constructor that translates digital code into functional micromachines (e.g., the 9.5 mm × 3 mm PrimeSwitch power relay capable of 150 A). He situates the technology alongside sci‑fi inspirations from Neal Stephenson’s Diamond Age and Snow Crash, explains why traditional macro‑scale manufacturing cannot reach the low‑micron regime, and outlines a massive, undefined total addressable market spanning data‑center power, micro‑robotics, and implantable medical devices. The discussion also touches on the need for a formal grammar (process graph) to compile atomic‑level designs, analogous to code compilation. Later, the episode welcomes Eli Manning and Michael Waldron to discuss the evolution of their comedy series Chad Powers. They recount the 2022 sketch that spoofed college football media, the improvisational style that drives the show, and the strategic planning for season 2—balancing a long‑term vision with audience feedback, talent sourcing from non‑traditional creators, and the changing landscape of Hollywood. They also reference the influence of science‑fiction on their creative outlook. Interspersed between these segments are brief news bites: a security incident at OpenAI where a hidden recording device was discovered, leading to the arrest of a Saudi‑national employee; and a preview of simultaneous high‑profile car launches from Porsche and Tesla, highlighting industry hype. Overall, the episode blends technical deep‑dives, entrepreneurial fundraising updates, speculative future visions, and behind‑the‑scenes media production insights, delivering a snapshot of how AI, advanced manufacturing, and entertainment intersect in 2026.

Chapters

More from Jordi

33:29
Podcast

Inflation Heats Up, Anthropic Investor Day, Tesla Roadster Mania| Diet TBPN

23h ago
2:07:31
Podcast

SELL EVERYTHING (Including Your Dollars), Tesla Roadster Hype, Valar Atomics VC Feud | Reed Albergotti, Bryan Cantrill, Daniel Kimminau

1d ago
32:28
Podcast

OpenAI Bugging Incident, Are Your Devices Listening? Xbox Launches Remix Lab | Diet TBPN

2d ago
2:39:40
Podcast

OpenAI Uncovers Spy Device, Apple x LG, Home Devices Tier List | Thomas Neckel, Kabir Jain, Danielle Axman, John Urschel, Nicolas Sharp, Jason Ballard, Erik Bernhardsson, Josh Tyrangiel, Aida Baradari

2d ago
32:12
Podcast

John Reviews The Social Reckoning, Muse Wonder, Apple’s HomeView | Diet TBPN

3d ago
31:48
Podcast

Crypto Going Bunker Mode, AI Mathpocalypse, Starbucks Explores Chipotle Takeover | Diet TBPN

1w ago
2:19:29
Podcast

Crypto Going "Bunker Mode", The Mathpocalypse, Starbucks Explores Chipotle Takeover | Rebecca Kaden & Michael Mignano, Nathan Benaich, Michael Sindicich & Healey Cypher, Moritz Stephan, Anastasios Angelopoulos, Zach Yadegari

1w ago
31:06
Podcast

OpenAI Math Breakthroughs, SpaceX’s $40B Nvidia Deal, Quant Firms Hiring Idea Guys | Diet TBPN

1w ago
2:26:15
Podcast

Some Math Problems, Arsenal-2, Porsche Mission S | Walter Russell Mead, Kat Cole, Tarek Alaruri, Tyler Niday, Scott Morton, Josiah Meyer, Aarush Selvan

1w ago
31:08
Podcast

AI’s Economic Impact, Warren Buffett Discovers YouTube, Mistral Launches “Le Chonk” | Diet TBPN

1w ago
2:31:15
Podcast

Le Chonk, Buffett Discovers YouTube, The Case Against AI Job Doom | Greg Fleming, TJ Parker, Joowon Kim, Rick Dungey, Dylan Field, Hardik Kabaria

1w ago
See all content