Mario GabrieleMario GabrieleFounder, The Generalist

Mario Gabriele's videos and podcasts

725 items

This week

generalist.com

About - The Generalist

20h ago
indiehackers.com

How Mario Gabriele Revolutionized the Newsletter Business - Indie Hackers

20h ago
@mariogabriele

Every sample at @periodiclabs sits in a circular holder, tracked by position.

1d ago
@mariogabriele

We are going to ship 1000x more software in the co...

2d ago
@mariogabriele

YouTube: https://t.co/gzU9ArgS5R Apple Podcasts: h...

3d ago
@mariogabriele

AI is not a biological agent, so if the environment is shaped according to its preferences, those preferences will be very different from ours.

3d ago

Earlier this month

@mariogabriele

“We’re really trying to create something that is like a successor to humans. The question is, what if we are successful?”

1w ago
1:07:06
Podcast

Jaan Tallinn would like us to survive

1w ago
@mariogabriele

The traditional model of science is simple: form a hypothesis, run the experiment, and watch it succeed or fail. @ekindogus, cofounder of @periodiclabs, thinks existing LLMs can't do this yet.

1w ago
@mariogabriele

always keep your eye on an underdog... :)

1w ago

September 2026

@mariogabriele

"A system that can literally engineer matter is going to be of key importance to everybody."

2w ago
59:49
Podcast

Periodic Labs: A chatbot walks into a laboratory

2w ago
@mariogabriele

speed of iteration of sigil and underdog is pretty...

3w ago
@mariogabriele

YouTube: https://t.co/mnlJ6sY5uz Apple Podcasts: ...

4w ago
@mariogabriele

SpaceX never set out to build a software platform. The product, as @scottgmorton put it, was simple: get things to orbit.

4w ago
@mariogabriele

Matan is one of the best founders I've met and jus...

4w ago
@mariogabriele

YouTube: https://t.co/mnlJ6sY5uz Apple Podcasts: ...

1mo ago
@mariogabriele

.@scottgmorton spent nine years writing control software at SpaceX. He left to build the software he wished he'd had.

1mo ago
@mariogabriele

Ex-SpaceX engineer @scottgmorton says one of the biggest keys to SpaceX's success is Elon Musk's willingness to make massive bets on his team.

1mo ago
@mariogabriele

"Nobody is going to bet their career on vibe-coding a nuclear reactor."

1mo ago
57:20
Podcast

An Ex-SpaceX Engineer on Elon Musk, Starship, and Building a $1B-Valued Startup (Scott Morton, Founder & CEO of Revel)

1mo ago

August 2026

@mariogabriele

Thank you to the partners who make this possible @...

1mo ago
@mariogabriele

Within five to ten years, @rooqster believes, stablecoin legislation spreads country by country and businesses fully grasp what tokenized money already is.

1mo ago
@mariogabriele

Thank you to the partners who make this possible @...

1mo ago
@mariogabriele

When people ask why a giant like Stripe or Visa won't just swallow the stablecoin market, @rooqster thinks they're missing the scale of it. They're picturing a new feature on a checkout page.

1mo ago
@mariogabriele

.@rooqster once asked a strange question: how much is the biggest bank in Jordan worth?

1mo ago
@mariogabriele

Thank you to the partners who make this possible @...

1mo ago
@mariogabriele

Thank you to the partners who make this possible @...

1mo ago
@mariogabriele

For decades, the world's biggest platforms have had global distribution by design. Instagram, TikTok, and Facebook: no distinction between markets and no asking permission.

1mo ago
@mariogabriele

"Money quantifiably is larger than AI. It's larger than food. It's larger than oil and gas. It's larger than municipal water supplies, government spending, defense. It's all of these combined."

1mo ago