This YouTube transcript excerpt lists six flavonoid agents (cromolyn, luteolin, EGCG, silymarin/milk thistle, quercetin, apigenin) discussed for mast cell control and histamine-related allergy issues. It also gives a brief definition of flavonoids as plant-derived antioxidants concentrated in colorful/rind parts of fruits and flowers and notes their role as stabilizers.
Flavonoid drugs? Well, cromolyn would be one that's commonly seen you get over the counter. Now for nasal use like, you know, nasal chrome. One is luteolin and that slows down a number of the triggering molecules. Constituent of green tea egcg, you've heard of that. That's another flavonoid that's used that way. Silymarin or milk thistle actually has some mast cell control. Quercetin. You probably heard of quercetin as a you know, people use it for allergies and other stuff. That's because it does many things but it's a mast cell stabilizer, apigenin. Now what are flavonoids? They're usually from part of the plant that is either the colorful part or if it's a fruiting plant, it's the rind part. And they are antioxidants and they're stabilizers to keep the fruit from going bad on the tree. Same with flowers. A little different biology with flowers. So that's why these largely come from fruit rind extracts.
