A clinician with 30 years treating fibromyalgia discusses a 2014 study of low-dose naltrexone at 4.5 mg. Results: 50% of patients improved much or very much, 20% saw no change, 10% got worse. He notes fibromyalgia shares immune problems with long COVID and chronic fatigue syndrome.
This is an interesting study, Journal of Clinical Rheumatology 2014, looking at fibromyalgia patients at a 4.5 bedtime QHS bedtime dose. 10% that were minimally worse, 20% didn't have a change, 20% improved a bit, 37% much improved, and 13% very much improved. Yeah, I've been treating fibromyalgia patients for 30 years at this point, and what we know is that there's rarely a single thing that makes a difference. And fibromyalgia is not completely analogous to long COVID, but it's It's a good surrogate in some places. Chronic fatigue, fibro, CFS/ME, they have a lot of the same sort of immune deregulation. They have a lot of the same under-the-surface problems that are going on. So that's why I say it's sort of a good surrogate.
