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Niacinamide is a precursor that your body converts into NAD+, the actual molecule that powers metabolism. Taking NAD+ directly may produce stronger effects than niacinamide, since it skips the conversion step.

Niacinamide is a precursor that your body converts into NAD+, the actual molecule that powers metabolism. Taking NAD+ directly may produce stronger effects than niacinamide, since it skips the conversion step.
Vitamin B3 comes in two forms. There is nicotinic acid, and then there is niacinamide. So niacinamide is the piece that is put into NAD. And so what you have is a stack of two niacinamide and then a joining bit of chemistry. Well, NAD is kind of the final step as a cofactor. So if I get NAD in its fully formed complex molecule instead of just nicotinic acid. Catenamide, I'm probably going to get a bigger effect from it. And indeed, that is largely true.