High-dose IV vitamin C requires two things: thorough patient screening for contraindications and lab work upfront, then infusion methods tailored to the individual to prevent side effects. Safety depends on assessment before you start.
In medicine, whenever you do any treatment, but especially an interventional treatment like IV vitamin C, and especially when you're using high doses of IV vitamin C, you want to do everything you can in 2 main areas to make the procedure as safe as possible. One is history, screening, and laboratory analysis of your patient. And then the other is administering the the IV in the best way physiologically and biochemically for that patient so that they experience minimal to no side effects.
