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Systemic autoimmune conditions like rheumatoid arthritis and multiple sclerosis create widespread inflammation that damages the gut's protective barrier, disrupting the tight junctions that keep the intestinal lining intact.
Systemic autoimmune conditions like rheumatoid arthritis and multiple sclerosis create widespread inflammation that damages the gut's protective barrier, disrupting the tight junctions that keep the intestinal lining intact.
Now, people say, well, Doc, okay, if I had Crohn's or colitis, you know, classic GI autoimmunity, obviously I would know I have digestive system problems. But just like chronic infections throw off your immune system, autoimmunity throws off your immune system. Now, you might think, how bad can it be if I have rheumatoid arthritis? I hate it in my joints. It's a synovial membrane attack in rheumatoid arthritis. How's that gonna affect my gut? Well, the The inflammatory nature of rheumatoid arthritis or the inflammatory nature of multiple sclerosis or any of the other, you know, 100 autoimmune conditions that people can have change the milieu in which your immune system works. And what that leads to then is an overall inflammatory state, and that can help to break down the membranes and the junctions in the GI tract.
