Short excerpt from a YouTube video (by Matt Kelly) explaining that mast cell activation in the digestive tract can produce a range of gastrointestinal symptoms — constipation, diarrhea, cramping, abdominal pain, malabsorption, and poor digestion — and that these symptoms often appear in people with mast cell activation syndrome or other mast cell disorders.
The digestive system is full of immune tissue. These are very sensitive to mast cell activation. So when we think about the digestive system and all of the immune cells that are in there, is that the digestive system? We may be having mast cell problems in digestive system that seem like other problems. The constipation, diarrhea, cramping, pain, malabsorption, poor digestion. All of those things can be from a number of reasons be part of mast cell activation. This is why we see a lot of gastrointestinal sequelae gastrointestinal problems with people who have mast cell activation syndrome. Mast cell disorders.
