Your digestive tract is packed with immune tissue that reacts when mast cells activate, causing constipation, diarrhea, cramping, pain, and malabsorption. These symptoms often get misdiagnosed as other conditions, but they're common in people with mast cell activation syndrome.
The digestive system is full of immune tissue, and these are very sensitive to mast cell activation. So when we think about the digestive system and all of the immune cells that are in there, is that the digestive system, we may be having mast cell problems in digestive system that seem like other problems. The constipation, diarrhea, cramping, pain, malabsorption, poor digestion, all of those things can be from a number of reasons, but they can also be part of mast cell activation. This is why we see a lot of gastrointestinal sequelae, gastrointestinal problems with people who have mast cell activation syndrome, mast cell disorders.
