NAC vs GlyNAC: Which is better for Glutathione?

24 Mar 2024 · 0 min

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In this segment, the speaker explains that GlyNAC—a combination of glycine and N‑acetylcysteine (NAC)—provides two substrates for glutathione synthesis, potentially raising glutathione levels more quickly than NAC alone. The speaker also notes research indicating that L‑glutamine can independently increase glutathione without the other two substrates. Overall, all three compounds—NAC, GlyNAC, and L‑glutamine—are presented as useful for boosting glutathione, with GlyNAC possibly offering a faster effect.

So if you take glycine and NAC, hence known as GlyNAC, you are going to have 2 substrates for glutathione formation. And since all 3 substrates are shown to raise glutathione levels, of course GlyNAC is going to maybe work a little bit faster to raise glutathione levels. But you also should know there's research that shows that glutamine, L-glutamine, will raise glutathione on its own without the other 2. So all 3 can be helpful.