What Happens to Cells When Mitochondria Are Damaged?

When mitochondria slow down or break, cells can't clear out metabolic waste. This buildup connects to cancer, immune dysfunction, and how some chemotherapy drugs work.
Chapters
If I do respiration with my lungs, I breathe good things in and I breathe some bad stuff out. Well, cell respiration, I take all these good things in, I have to have bad things go out. If my mitochondria slow down, I build up cellular metabolic garbage. So if the mitochondria are damaged, slowed down, whatever euphemism you want to use, a slowdown in the ability to move the garbage out of the cells occurs. Now that, as I say, generally we don't wake up one morning and think, oh, I'm not cellularly respiring as well. And I'm not moving the garbage out like I ought to, but that does build up over time. And there's actually research now, a lot in the cancer world, looking at movement of, you know, immune cells and chemotherapy and all kinds of other stuff that really backs this concept up. It's not like it automatically happens and it's always perfect. The slower your mitochondria are, the more backup you're going to have.










