In this brief medical explanation, the speaker identifies individuals with an inherited deficiency of the enzyme glucose‑6‑phosphate dehydrogenase (G6PD) as a group that should not receive high‑dose vitamin C, an oxidative therapy. Because G6PD‑deficient red blood cells cannot handle the oxidative stress, high‑dose vitamin C can trigger hemolysis, potentially leading to hemolytic uremic syndrome, severe organ damage, and even death.
Are there people who shouldn't get high-dose vitamin C, which is an oxidative treatment? Well, people with an enzyme deficiency, which you inherit, called glucose-6-phosphate dehydrogenase enzyme, so G6PD enzyme, if they're deficient in that, they cannot have high-dose vitamin C. Why? Because they would have hemolysis, which is their red blood cells exploding essentially, which is obviously very bad for you and can trigger hemolytic uremic syndrome and many other bad things, including death. Death.
