55: Can the “Love Hormone” Heal Your Skin? – The Science of Oxytocin & Emotional Beauty with Dr. Sabrina Fabi

We are talking skin care in a pretty unique way. On today's episode of Modern Thyroid and Wellness, we are chatting with Dr. Sabrina Fabi, who is a board certified dermatologist, cosmetic surgeon and the co founder of Exomd Skincare, the world's first mood suitable designed to help women reclaim balance, confidence and skin vitality during life's hormonal shifts, which I know we've all been through. She is internationally recognized for her research and patient care at the intersection of aesthetics, wellness and confidence. And guys, I think you're going to be surprised by some of the things you hear in this episode. And towards the end, we realize that we should probably get you an affiliate code, so I will insert that at some point throughout the interview as well. Let's dig in.

Welcome to Modern Thyroid and Wellness, the podcast that explores the intricate dance between health, wellness and thyroid unraveling the threads that weave our vitality together. I'm your host, McCall McPherson, and I'm so thrilled to guide you on this journey to optimal wellness. I'm so excited for this conversation today. We have actually never talked skin. We've never chatted about this topic at all on Modern Thyroid and Wellness. So, so welcome to the podcast.

Thank you so much. Thank you for having me. I'm still so honored to be with you.

So talk with me a little bit. You know, one of the ways that thyroid dysfunction, thyroid disorder manifests is it impacts our skin, our hair, our nails. Talk with me a little bit about the thyroid skin connection and how that might manifest in a dermatologist's office. What you guys are attuned to. What makes you think, oh, well, maybe this is a thyroid problem?

Yes. So whether one has hypothyroidism or hyperthyroidism, it manifests a little differently both on hair, skin and nails. I'll kind of walk through a little bit about what I think some of the reasons why we usually pick it up as dermatologists. Specifically when it comes to hypothyroidism, I find that one of the telltale things we see is women complaining of hair loss. And it's part of the panel we do when we're trying to rule out why someone may all of a sudden have hair loss. And when someone has been on a new medication or they just were pregnant, you can generally get hair loss, something we call telogen effluvium, like a temporary loss of hair that can happen anywhere between two to three months after the initial insult, but it may not always be associated with those types of conditions. It can also be associated with hypothyroid. And so we generally check a thyroid panel to make sure that that's not one of the culprits. Because if you don't fix it, then, or we don't send to a primary care doctor or someone that can potentially help with managing the thyroid disease, the hair is not going to grow. No matter how many lasers or red caps or oral supplementation may want, one may take. And then I'd say along with that is usually loss of the lateral third of the brow. And so that's something that when I notice that in patients that might come in for their injectables or for their laser treatments, that's usually a cue for me that we see specifically with thyroid disease that we may not necessarily see with other reasons why someone gets hair loss, which is new drug, postpartum, recent surgery or illness, et cetera. So I'd say that's with hypothyroidism, hyperthyroidism, although you can have hair changes not. And it's more like finer hair that we start to notice that folks start to shift into a finer hair. I can't say that that as common of an issue for my hyperthyroidism patients. I find that exophthalmos, which is where the eyeball itself protrudes out of the socket, that's usually when I fl. And my patients don't notice it. So this is interesting. Patients don't notice that they might be hyperthyroid. They don't actually complain of this. They complain that they feel that they have hollowness under their eyes. And that's because your eye now is protruding out and creating more of a negative vector with the cheek. And so your cheek looks more hollow. But it's not that you have volume loss under your cheek. It's that you have the eye actually coming out.

You know what I love about this and appreciate so much is people are coming into you for either, like, a dermatological issue or even for, like, Botox or fillers or, like, esthetic reasons. I so appreciate that you are like, taking a step back and being like, does this person have exophthalmus? Like, maybe they need to get a workup or, gosh, I really see the outer portion of your eyebrows because I think we deserve that. But in so many aspects of medicine, that actually isn't happening at all. They're like, well, this is someone else's problem. I'm just going to leave it to them and just let them handle it. And women need that screening for thyroid because it's such a pervasively common issue that obviously also gets missed for often years, if not decades. So I love that you are keeping your eye out, and you're the first line of detection for this. It's really, really powerful, and I think it can impact so many people in a positive way.

Yes. Well, I mean, if people are coming to see me to look better.

Right.

I mean, there's only so much I can do if metabolically, you're not optimized.

Right. And the hair loss piece, like I tell you honestly, women will come into our practice and not be able to function. Like, they cannot get out of their pajamas. But if they have hair loss, they're like, I don't even care. I'll stay in bed all day. Please just fix my hair.

You know that. I mean, that's the power of dermatology. I mean, that's why I'm a dermatologist. Right. Because usually systemic disease does manifest on the skin, and it's not until it manifests on the skin that it actually makes someone come in. And so it's really like our gateway to understanding what's happening internally. And there's a lot of. For people that want to diagnose things like rare conditions or metabolic conditions, the skin tells us a lot. So that's. That's the reason I love derm.

Right. Everything's so interconnected. It's not as separated as we often think about it being. Right.

Correct. You're absolutely right.

Talk with me a little bit about hormone balance, hormone imbalances, how that impacts skin. Obviously, men, per usual, have it kind of easy. They, like, coast through life in a lot of different ways. But women, we have seasons and different experiences hormonally at different parts of our life. So I'd love for you to take me through some of the ways that that manifests on our skin in each of these seasons.

Yes. So I think perhaps they're all interconnected and they actually can kind of manifest the same way. So whether you're postpartum, sometimes when you're postpartum, you can actually have a. There are reports of women going into, like, a thyroid crisis after you have delivered a baby and that shock. So. But you don't know this because you're experiencing the hormonal crash, no longer being on the high of estrogen, oxytocin, and progesterone that you were on when you were pregnant. So no one knows why you're. You know, you feel a certain way. And thyroid disease can absolutely impact how sluggish or sleepy you may feel if you're hypothyroid and your mood as well. But you're also navigating the crash from the hormones of pregnancy. So that's, you know, where that's one place where one of the shifts happen for women and hormones that I don't think we talk a lot about. Menopause is definitely having a moment. And so I'm so glad that there's that awareness around it, because when you go into perimenopause, you start to have, most notably, a shift in progesterone. And progesterone stimulates your sebaceous glands to create oil. So the skin may not be as oily or it may be more dry than it used to be. And also, as a function of age, just like any organ, you can also start to see a decrease in whether it's thyroid hormone being secreted T4, or the ability of that T4 to become T3, which is a more active hormone. And so when you don't have that happening, you can also have dry skin, because thyroid hormone is able to support your gland production, your sebaceous and your eccrine gland production, so you can have dry skin there as well. And so all of these things are happening at the same time. You don't know what to attribute it to. You can also start to have a little bit more sleepless nights because of the progesterone. You start to wake up at three in the morning. You feel a little bit more tired.

I woke up at three in the morning. Did you hang out in my room last night? Like clockwork. So many of us.

And so you don't know if it's because of the thyroid disease or if it's because of the progesterone shift. Right. And so because hypothyroidism can absolutely make you tired, and so you start to kind of have both things happening, and then you go into menopause. And now a significant decrease in estrogen definitely causes an increase in what we call transepidermal water loss. So the ability to hold moisture into the skin, so it's no longer as much your sebaceous glands that create oil that are not necessarily working as well. Now your ability to actually hold water is disrupted. So your skin is absolutely dry. It gets thinner because you don't have that estrogen to fertilize the cells that create collagen, elastin, hyaluronic acid. And so as a result, your skin gets thinner and more lax. So it looks a little this if you can imagine, coupled with hypothyroidism can absolutely make someone feel like their skin's really dry and can manifest even with hypothyroidism, like itching, but with menopause itself, not necessarily. And then if you couple this, if you have hyperthyroidism, you can have these flashes of heat, you get really hot. Now, if you're going through menopause, you might attribute all of these vasomotor symptoms to a decline in estrogen, when it actually may be a thyroid dysfunction. So I think it's really good to be in the care of someone that's more. More holistically looking at your hormones and all the parts of you, because all of them are shifting at about the same time, unfortunately. And it's a perfect balance of these things that can participate in making someone feel and look whole again.

Totally. I think it's so confusing for women. Like, one of the most common questions I get is, like, well, how do I know if this is my thyroid? How do I know if this is my hormone? And the answer is, like, look like we probably need to get data on all of it and track it, ideally before you go into, you know, immense amounts of perimenopause and things, so we can detect those shifts so early on. Talk with me a little bit about, you know, the wear and tear that these processes have on our skin barrier and is there things that we can do to protect it? Because you can tell us too, like, what role does our skin barrier play in our overall health and all the things.

Right. So our skin barrier is actually very important in our overall health. The skin's function is to protect you from organisms outside infections that could potentially penetrate. Right. That's. So it's your greatest defense mechanism in that way. And then there's a lot of immune surveillance in the skin to protect you from any type of organism. You can really, actually learn about a lot of it. When we just even look at somebody who's atopic or who has eczema, where you already genetically have a compromise in your epidermal in your barrier, like, that's like the. That's at the pathology end. Now. You take somebody who's been normal, and then you add the fact that they start to get hormonally depleted, and then this has an impact on someone who is otherwise normal, all of a sudden, their skin is dry. And it's not just. It can be, you know, vaginal tissue, it can be your space tissue, it can be your neck. It gets thin as a result, because of this epidermal compromise, it also feels very, very dry. Now, you know, this might be beyond the scope of what we're talking about today, but some women, you know, will complain about that dryness causing pain with, you know, sexual intercourse and other things. And that might bring them in when it comes to like facial skin and body skin, which is more what I, what more of what people come into me about. In dermatology, we definitely do learn and study a lot about vulval vaginal disease, but that's just not the focus of my practice. But it will manifest when your skin is dry. It's an inflammatory. It's a cue for your second layer of your skin, the dermis, to like increase that immune surveillance because the barrier has been compromised. So it's like your immune surveillance goes up. So it's a little bit in a more hyper inflammatory state. This can participate in making it look a little bit more red where you may not have had facial redness before or a little blotchy. And that's because it's in a more inflammatory state. And with age, our antioxidant reserve in our skin diminishes starting in our twenties, believe it or not. So when you are in the sun and you've gotten that UV exposure or you did a run and you are in a polluted city with a lot of particulate matter in the air, all of those insults on your skin are not able to be cleared as readily because you don't have the antioxidant reserve in your skin. So your skin is dry, red, irritated, and now it's subject to more insult from anything that you expose it to. So that's really what a barrier that's compromised can look like.

I love it. And I love that we're finally talking about the skin barrier because honestly, I didn't even hear much about it until, gosh, I don't know, a couple years ago. So it's so cool to learn more and have these conversations evolve. You know what I really admire and appreciate about your approach is again, it's like this holistic, this integrated view of skin. And it's not just so segregated. And you really consider how skin is impacted with our daily life and our hormones and our age and all the things. And I want to transition in a minute too to Xomd because it's such a unique product and I think our people are going to love to hear about it. I want you to tell me too, like what are some daily rituals, some habits that people can have to improve their overall Skin, including skin care as well. But to restore a sense of feeling like themselves. Because for women, that's so much of our journey is like staying connected to feeling like we are ourselves in our body. And a lot of times that's challenging. So it's. Give us some tips and insights in your viewpoint of what we can do to help with that.

I'd say that there's probably nothing better than sleep for your skin.

Amen.

And so that's why the hormone stuff affects it so much, because it's beyond your control. Unless, of course, you have the control to go try to work on it and fix it. But it's. It's something that you know that was. You were hijacked, right. It's not like you did it to yourself. So sleep is probably the best thing because if you don't sleep now, you have cortisol levels going up and wreaking havoc in an environment that's already compromised with perhaps low or high thyroid hormone, with perhaps a decrease in progesterone, with perhaps a decrease in estrogen, with perhaps a decrease in testosterone. So, like, if the one thing you can control is your sleep, then that's probably the best thing you can do for your skin. That's one of the best things.

Right?

A dermatologist will tell you protect yourself against UV damage, and I agree with that. But sleep plays a big role because even for the UV that you get exposed to, if you have high cortisol levels, you. Your skin is not equipped to scavenge the free radicals from the extra UV that comes in from the particulate matter, from pollution that comes in because it's compromised. Right. So how can you achieve good. Well, other than seeing an integrative medicine doctor to be able to be optimized. Well, good sleep hygiene. So not being on, you know, a computer monitor or something that is emitting blue light, you know, ideally within three hours of going to bed, not even having that in your bedroom, turning that off if your bedtime's at 10, turning that off at about 7, trying to minimize just that, light pollution in your room. So if you are in a city like Chicago, which is where I am right now, or like having dark blackout shades so that you're not getting that white light from outside, that can also affect your sleep quality. So optimizing yourself in a way so that you can get as good of sleep as possible, that also exercising regularly supports that sleep hygiene. And then I would say second thing is really protecting yourself from UVA and uvb. Not just uvb, but UVA as well, because that penetration penetrates a little deeper into the second layer of the skin, and that's what ends up breaking down your collagen and elastin and causing the lines and wrinkles over time. So I would say with that, using a physical blocker, not like chemical sunscreens, but things that have zinc oxide. The same stuff that's in my baby's diaper rash cream, right? Which can look white and pasty, but is really protecting you. And now there's micro ionized forms of that so that it looks like a little more sophisticated and it can come with a tint. And the tint, the ferric oxide, actually can help block more of that UV light. So I'd say, like, those are great things to do preventatively. But then what you put on your skin makes a difference as well. There's more and more awareness around clean beauty. The products that you put on your body, right? You want things that ideally don't have parabens, sulfates, fragrances, things that you can potentially develop an allergic reaction at any time in your life. It's a misconception that something that you tolerated forever, you can now all of a sudden, like, not. You'll be able to tolerate forever. That's not true. You can develop an allergic contact dermatitis to something at any point in your life. So you want to make sure that you minimize contact with things that you don't need to be in contact with topically. Like, you're putting. What would you put on your baby, basically. And so that was the impetus for me when creating a product line that whatever it was in the vehicle was as clean, that was as important as the active in it that was gonna have the effect.

I love that. I mean, we need that and we need to have these conversations. Gosh, I wish we knew about this like, 20 years ago. For us, selfishly, I think, like, this next generation is at such an advantage than we were, for sure. At least it appears that way. My kids that are like in middle school, high school, I was like, awkward, ugly, not ugly, but definitely not, not blossomed. And they just like never go through that stage now. They're just in such such a unique situation compared to us.

It's.

It's an interesting time to watch them grow up. So what you guys have accomplished at XOMD is really unique. And I consider myself a skin care. Like, I'm into it. Like, I stay up with it. I love unique products. I love clean products. I really explore this topic. It's somehow Become niche for me. I had no idea this would happen a few years ago. But what XOMD has done is unlike anything else I've ever encountered. So I want to open up this conversation and I would love for you to talk with us a little bit about the concepts of neuro cosmetics, moodseuticals. Take us through this idea because it is so unique and I've tried your products, I absolutely love them. I've tried them all. I literally used the face wash this morning. I need to stock on the other ones. But I absolutely love them. So take us through this idea. I want to share it with everyone.

So I noticed that my skin crashed after I delivered my baby. Right. So I like during pregnancy and being in a static medicine now for over 15 years during pregnancy I had done no aesthetic procedures because you can't when you're pregnant. And I look younger and I look glowing and I hadn't done my Botox for, you know, over like seven months. And I was sleep deprived because my baby was in all forms of positions that wouldn't allow me to sleep. So I was sleep deprived and had a, you know, a human growing in me and I yet managed to look better than without being pregnant. So I was wondering, like, how is this possible? So is it all estrogen? It's not all estrogen. You know, sometimes there's definitely a hot molecule or a hot hormone and that's great to shed light on something so that we can learn more about it. But I think it's the interplay of everything that's more important. And so my partner and I, Steven Dayan, who is a facial plastic surgeon and someone who's done a lot of work on like the impact that aesthetic procedures have on mind and mood. Right. Because that's probably why I'm so integrative in my approach, because you can only do so much. But what's happening in the person's body physiologically and then mentally can sometimes have a much greater impact on their perceived outcome of the procedures that we do. So it was a beautiful blend of our philosophies, what I was physically going through and then what we both philosophically believe. And so we started kind of examining what's happening uniquely in pregnancy and uniquely in pregnancy, although you definitely have a spike in estrogen that you've never had in your life. And progesterone definitely goes up as well. There are some other molecules that start to go up, testosterone a little bit. So not as much, but definitely oxytocin. So oxytocin goes up and oxytocin is a molecule that releases when we cuddle, when we're in love. The reason why people say, oh my God, you look so good. Are you in love? Like, where does that come from? There's usually a truth behind many sayings. So perhaps the same reason why I look good when I was pregnant. And so we started to evaluate this a little more understanding why it wasn't available topically, as some of these other neurohormones or peptides are. And when we evaluate oxytocin, there is actually a great study that had come out in 2021 from another dermatologist that probably noted the exact thing we did, which is that people that had higher intrinsic oxytocin levels on average looked about three years younger than people that had same age counterpart variables. Like, in fact, some of the people that had more sun exposure still look three years younger than their same age counterparts that had low oxytocin levels. So we were like, wow, this is. And I believed it. I looked like there was like a, like almost a more youthful look to my. Just not only my face, but my skin. And the reason why some people look dewier and more radiant. So we started to explore this molecule and talked with a lot of neurobiologists to try to sort a peptide that could mimic oxytocin. Because the beautiful thing about oxytocin is that you have receptors right here on your top layer of your skin, on your keratinocytes, so it doesn't need to be absorbed like many topical formulations do, in order to bind and have its effect. So after searching for something that could mimic and bind to the receptor, we started to put it to the test. Could we potentially get the same effect that you see in someone who's in love or pregnant and mimic it in somebody who's not necessarily in either one of those states? And because sometimes actives are really interesting. But when you put it in a formulation, a vehicle, it's not stable, or there's not enough in it to have the clinical effect you desire, or the vehicle cancels it out because there's some type of interaction. So you don't really know until you go into the form, into the actual testing state with a lot of people don't do in cosmetics, you don't have to. And when we did this, we found, we did a placebo controlled randomized trial. That means that the half the folks were on xomd, the other half were on the vehicle, this clean vehicle that I told you about, but with no ox factor so no peptides that bind to the receptor. And when we looked at like skin metrics after four weeks of use of a serum moisturizer and cleanser twice a day, we found that those that were on XOM D statistically significantly had less dry skin, less red skin, which we would anticipate because it's an anti inflammatory like neurohormone. They had more evenness in their skin tone and they also had more dewiness and radiance, which we expect, which we see in pregnancy and when people are in love. And as like a safety check, almost as like a sanity check. Lines and wrinkles did not improve at four weeks. And we wouldn't expect lines and wrinkles to improve in four weeks because this is not, it's not able to stimulate the fibroblast to create enough collagen and elastin in that short of a time. So we knew that the data was good, otherwise that would have been off. So when we crossed the placebo over to the being on the xomd, those that were on XOMD for eight weeks versus those that were only on it for four weeks, being on it meant that all those metrics were even better. So they were significantly better redness, dryness, evenness, dewiness, radiance than those that were on placebo after eight weeks of use versus four weeks of use. So there's definitely a cumulative effect of being exposed to the ox factor. And so we were able to mimic similar things that we see in those that are in love and those that are pregnant. When it comes to skin quality, that.

Is so damn cool. It is just so cool. And I'll tell you like I vividly remember there's a colleague of you and I that we both know, a shared, a shared friend. And I remember texting her after I flew somewhere for an interview and I was so worried I was going to get there and I was going to look all haggard and just dry. Airplanes dry me out like nothing. And I'm a dry girl, right? I'm a thyroid lady, so I'm dry. I get there and I texted her that night after I got to the hotel and I was like, my skin feels so incredibly hydrated after a three and a half hour flight. And I only used XOMD that day. And I'm like, this is incredible. Just from an hydration standpoint to withstand the dryness of an airplane. I showed up to my interview the next day, my skin never looked better. Like it literally really didn't. And I had been using it for A long time. But I had expected, hey, I'm going to show up and my skin's going to be dry because that's just how it is after I fly for a long time. So I can definitely vouch for, for that. And the cool thing too, that I love that you guys consider is how, and I've experienced this myself kind of for the first time in my life as a woman in her 40s, that's now kind of investing in my skin as I age. But how that impacts how you feel in the world, like your relationships, your confidence, your quality of life. Tell us how those two things interplay.

Well, we see it all the time. We see it in aesthetics, right? You do a procedure, someone looks good and then they feel better. You even see them in their after photos. All of a sudden their hair is down and they have jewelry on and they're standing up a little bit higher and taller. And that's because there's no doubt that it's beyond something superficial, just like treating some redness or dryness, you have an impact on the way they feel about themselves and their overall confidence. And that's something that we measured in the trial. How much more confident do you feel? Because a lot of women don't want to have to wear makeup, and you want to feel confident makeup less. And so in the trial, 87% of those that were on X OMD felt more confident after being on the product line. So it definitely has an impact. And that's really, in the end, what we're. We're trying to make people feel better about themselves, whether it's with injections, lasers, or in this case, something that's more accessible for people, which is a topical skincare line. We also looked at first impressions, right? Because people always, I've noticed, even after I do procedures are like, no one noticed, but I'm like, well, you wanted a natural result, but you kind of want to be noticed, right? So we found that those that were on it significantly had a significant more rated higher in first impressions than those that were not on it. When we took images and like, put it out on survey monkey to like about 200 lay raters. So a random person on the street will perceive you and like 5 out of 10, 8 like first impression metrics as more attractive, desirable, financially successful, it was really interesting. So these are validated first impression skills that we use in many of the injectable trials that we do. These same lay raters on average rated these people looking three years younger. So it was interesting that here, like the three years, I mean, for it to be the exact same thing that we saw in the original Haver trial in 2021 was interest that it was able to reach that same outcome, that same number. So it makes people feel and look more youthful, which is great. And then we had fun and we decided, okay, should we also. When you have higher oxytocin levels, you tend to feel closer to your partner. You're more trusting, you're more confident in yourself. So you. If we asked people that were in romantic relationships how the relationships were going intimately, and on 18 out of the 20 questions that were asked, which are like validated sexual satisfaction scales that are used in other parts of medicine, the XOMD users were positive where placebo was zero. So we were like, wow, out of all of the data, that was actually the most profound data that we saw. So it definitely mimics the effects that one would have if they were in a state of having higher oxytocin levels.

That whole journey of like gathering that data had to be so fun. Like that just had to be the adventure of a lifetime because what cool things to unravel as you look at this product and how it can change people's life and how they feel about themselves and their relationships. Like that is so.

Oh yeah. I mean, for us, well, it was a little nerve wracking because as an owner of a company, you can't participate in the trial because they, you know, they always want you to be. They want data to be unbiased. So we had somebody else conducting the trial. So we were like, we didn't.

Pins and needles. Yeah.

We didn't know what was going to come out of it. So to uncover all this data once we had it was like, wow. I mean, it really speaks to like what we both philosophically believe is that we should. The reason why people do these aesthetic procedures is to feel like the best versions of themselves, to feel like themselves again, not necessarily to chase 21 again. Sometimes being 21 wasn't the time that you felt the best anyway.

It's.

It's just to feel more empowered. And so we definitely got that. And it translated into just in first impressions that they had with strangers to how they showed up in the relationship. So for us, there's nothing more gratifying and powerful because that's what we try to do every single day in our aesthetic practices.

I love it so much. I really do. Thank you for your work. Like, thank you for being interested and invested in women feeling powerful, beautiful like themselves. What rewarding work that Is truly such a cool thing to like dig into. I had already known lots about XOMD and heard so many incredible things. But to like really understand the whole process is really a delight. Tell listeners a little bit about where they can find out more about xomd, a little bit about the products. There's. I know, I know, I've tried three, but give them a little bit of the general spill.

Yes. So presently we have three products because we recognize, you know, that sometimes simple is easier to comply with. And so we have a cleanser. When I created the cleanser, it was intended for my patients that have sensitive skin because I have like third of my patients have sensitive skin and it's like you put anything on them and it's too drying or it's irritating or it makes them red or so I literally wanted it to be able to be used in someone who I've done a CO2 resurfacing on like post op day two. And that's what we created. So it has that and we use that twice a day. It's gentle enough to use on resurfaced skin, but good enough, practical enough to actually get the grime off of your skin. Because in my resurface patients I'm trying to get that dry blood off of their face. So it's actually a lot of gentle cleansers. One of the frustrations as a dermatologist is that they don't take anything off of your skin. So you need something to take it off but not strip your oil off of your skin that already might have, you may already have dry or sensitive skin. Then there is the intoxicate serum. And so here it's a serum that has beta glucans. So a lot of serums in our space, the vehicle is just like water. It doesn't actually do anything to hydrate you. It may have an active in it, but it doesn't do more than just deliver the active. So it's either watery or it's more in a dimethicone base which is a synthetic derivative of a silicone that in some countries aren't favored. So I didn't want that. So I wanted something that actually could serve a purpose if somebody has oilier skin to draw in that ox factor, that proprietary peptide that binds to the oxytocin receptor. And then on top of that we layer the aroused moisturizer here. This also has the ox factor that has that active, that has the anti inflammatory effects as well as increases dermal water retention. But we trap the water with glycerin because a lot of times things are moisturizing, but they vaporize or they don't actually trap the natural water that you have in your skin. In your skin. And this is intended for someone who has a little bit of barrier repair issue so that it creates that seal. And so that's, that's a three step product line. That's what using it twice a day is what ended up creating the benefits that I just talked about in the trial.

That's exactly why I had the profound experience of my skin staying hydrated even though I went on a long flight. How fast? Fascinating. You know, and like I use good skin care before every flight, but like it was significant. So cool. And people can find out more at Xomd and tell me about socials and things too.

So you can go on xomdskin.com and then we're also on Instagram at Xomd skin, we're on LinkedIn, we're on Facebook, we're on TikTok. But that's where you can kind of learn more about the product and if one decides also purchase it, I love it.

Well, thank you so much for taking the time out of your day to be here to share all of this with us. Thank you for your dedication to women and helping us feel more beautiful and in our own skin. I just really appreciate it and I'm excited to get the word out.

Thank you, McCall, thank you for having me. Such a pleasure. And thanks for all you do to also increase knowledge around hyper and hypothyroidism, just thyroid disease, because sometimes people all just think that it's all related to progesterone and testosterone and then there's other hormones at play.

Amen.