McCall McPhersonFounder, Modern Thyroid Clinic.

Combining Cytomel with Desiccated Thyroid

9 Jul 2024 · 1 min

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1:05

A short YouTube clip (speaker: McCall McPherson) describing clinical/personal practice of combining Cytomel (liothyronine) with desiccated thyroid preparations (Armor, NP, Atheiza) for patients whose labs show relatively high inactive T4 versus active T3. The speaker explains that stress can impair peripheral T4→T3 conversion and increase reverse T3, and that adding Cytomel increases the active T3 proportion. The speaker provides a rough prevalence estimate that about 25–30% of desiccated-thyroid users may need this adjustment.

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Good morning guys. So I combine cytomel with desiccated thyroid like Armor or NP or Atheiza. Whenever patients basically their labs show they have too much T4 inactive hormone compared to T3 because those desiccated thyroid medications are mostly all inactive hormone with some active hormone. Not everyone can handle that ratio of inactive to active. I am one of those people, especially when I'm stressed. My conversion does not get enough T3 from that and I often get too much reverse T3 inhibitory hormone. So in those cases I often add in cytomel to armour or NP and therefore skew the ratio of T3 to T4 or active hormone to inactive hormone. If that makes sense. And I would estimate probably that's necessary and maybe 25 to 30% of people who are on desiccated thyroid. Rough estimate, but yeah, I hope that's helpful.