GRWM Live thyroid, weight loss and hormones Q&A

McCall McPherson answers live questions about thyroid medications like levothyroxine and Armour, Hashimoto's treatment, hormone imbalances, and GLP-1 weight-loss drugs. Topics include estrogen dominance, hair loss from semaglutide and tirzepatide, and supplements like DIM and selenium.
Chapters
It. Foreign. Hi guys. We're going live to answer some questions if you guys want and hang out a little bit. I'm live on Tick Tock and Instagram so if you guys want to hang out and ask me thyroid hormones, metabolic, weight loss, all those kinds of questions, I am totally here. Shoot all thanks for the hearts Tick Tock. I love you guys. I hope yalls week is going well. Good morning. Good morning. Good morning. Thanks for all the love. Yeah y' all give me all the love so that other people know that we're here. Because I scheduled lives weekly on Tick Tock for Fridays I thought and I actually scheduled them for Thursdays so I messed up yesterday. Could not go live on TikTok. Had other meetings during the time that I accidentally scheduled them for. So yes, please give me hearts and shares and all the things so that other people know that we're here today and not yesterday. Normally this starts out pretty chill. Normally there's not too many questions in the beginning and then it gets crazy. So if you guys have questions, ask them early on. I just got one thoughts on Livoxyl. So Livoxyl is a type of thyroid medication that is the same class. It is T4 based or levothyroxine based. So it's all in active hormones. It's dependent on your ability to activate those hormones, which most people don't do well, which is why people continue to feel crappy on levothyroxine. So if you are still having symptoms and you're on luboxyl, I would highly recommend you consider talking with your doctor about adding in some active thyroid hormone and not relying completely on inactive hormone. Those are drugs like cytomel, Leothyronine. Good morning. If cutting out dairy helps, do you think you have to be dairy free forever or can you reintroduce it? A lot of people can reintroduce it. Let's talk about this. Thank you for the hearts, y'. All. So if Hashimoto's is driven by inflammation, right? So inflammation is caused by a lot of things, but one of the number one, you know, food that I see is actually dairy. So I want you to think about inflammation like water in a cup or yerba masay in a can. Every bit of inflammation you get is a little drop of water in that cup. You do not experience symptoms or autoimmune disease until the cup overflows. Okay? So we don't need to have the cup be completely empty. We need it to have a level. Thanks for the hearts that can handle inevitable drops of inflammation without it triggering this eruption of overflow. So let's say you go dairy free. I would recommend you measure your Hashimoto's antibodies before and then three months later, see how they change. And you are trying to get rid of a lot of the water in your cup in those three months. I'd really recommend at least six months. Well, you're going to lower the water level, right? That makes you more resilient to these inevitable drops of inflammation. And you have to find, over time, the tipping point. How much of this tall, how much of this can I tolerate before it triggers that eruption of overflow? How long can it take for LDN to decrease on T decrease TPO antibodies? It. I tell people it continues to reduce inflammatory levels for up to 18 months before it kind of levels off. Do you see other patients or a lot of patients with hypothyroidism and Hashimoto's with depression and anxiety? Why? Absolutely. So hypothyroidism itself causes depression, depressive symptoms. It just kind of slows neurotransmitter production and can lead to depression. I see Hashimoto's highly poorly with anxiety. Do you take other meds with Levo? I do not take Levo. I take Armour and lyothyrenine or Cytomel. But I have lots of patients on Levo plus lyothyronine or cytomol. Do I recommend lyothyrenine Even if your T3 is in range? What is in range? Because most of the time people are not in an optimal level of T3. Even if it's in range, you guys can be complete. What I want you to know more than anything is y' all can be completely debilitated and be in a normal range for thyroid function. Okay? You want to be optimal. You have to be optimal to live your life, to enjoy your life, to thrive, to function well and not just be in survival mode. What is the connection between low progesterone and hypothyroid? Great question. So when you have a thyroid disorder, your hormones shift, right? You start to lose some hormone production in more significant cases. That's why women stop having periods, right? So there's two hormones that begin to drop earlier in that process, and it is progesterone and testosterone. We have limited amounts of both of those. As women, we don't have like a ton. Sorry, guys, don't love this lighting. We don't have a ton of it. And so globally, hormones start to drop, but the first things that drop are the hormones. We have the least amount of progesterone, testosterone, estrogen, we have a lot of. So that usually ends up dropping last. And it leaves us in this estrogen dominance state, which is why so many women with thyroid issues have estrogen dominance. They end up getting low progesterone, low testosterone, and then they have a lot of estrogen by comparison. Hi, Charmaine. Good morning, Sarah. How can I go gluten and dairy free when that's all I crave and I'm a picky eater? You want to hear something interesting, guys, about craving gluten and dairy? So when you go to the hospital and you get IB Morphine. It's called dextromorphone. That is what ibmorphine is. Do you know what dairy breaks down to into your. In your brain? Gleamorphone. Excuse me? Casomorphone. Gluten breaks down into gleomorphone. And I'm sure I'm mispronouncing that, but that is a morphine derivative. It is as addictive as a pain medication. So your body craves gluten and dairy. Guess what happens when you stop eating it? You don't really care about it anymore, unless it's the cream in your coffee, and then you're sad every morning. But otherwise, you're physiologically addicted to gluten and dairy, and you don't want to be like, you just need to break that cycle and you'll not crave it nearly as much. Okay, when might you reduce TSH if T3 medication is improving? I don't think I quite understand that question. Can you ask it in a different way? Let me see. Let me go back to TikTok for a minute. When will Illinois be on the state list? It should. I mean, literally, we're waiting on one thing in Illinois, and Illinois generally doesn't take so long. It's taking a little longer than we expected. Trying to think. I do feel like our. One of our nurse practitioners, Hillary, is licensed in Illinois, but she went on maternity leave, which is why I think we had to pull it. She comes back in October. So I think the latest. Don't quote me, but the latest it would be is October, but we have other clinicians getting licensed there as well, literally for that reason. So that, like, if someone goes on maternity or their schedules booked, we have backup plans, so it shouldn't be long. I thought women, even though we have less testosterone than men, have higher levels of testosterone than Estrada. No. So women's optimal level of testosterone is 35 to 65. Women that I see with thyroid Problems not uncommon, that they have less than 12 level of estrogen, which, I mean, excuse me, testosterone, which is undetectable. I'd say average is like 12 to 20. So most women are walking around highly deficient. Our level of estradiol is usually, you know, anywhere from about 65 to 300. And obviously it wildly fluctuates during our cycle. Right. How do you know without labs if you're estrogen dominant? Good question. I can tell you guys the symptoms of estrogen dominance. I encourage you to get labs, and I can tell you how to do that too, if you want. But symptoms of estrogen dominance are anxiety, irritability, agitation, insomnia, heavy periods, crampy periods, moody periods, dysregulated cycles, breast tenderness, cramping at ovulation. That's for women who have a period. All those symptoms of anxiety, irritability, agitation, insomnia, all are worsened leading up to your cycle. They're building, building, building, building. You start your period and you're like, oh, my God, why was I so angry yesterday? What was going on? And it's because you're estrogen dominant. Why do I keep getting in fights with my husband every month? That kind of thing. Postmenopausally, women generally don't have estrogen dominance, but if you get too much estrogen postmenopausally, like, from supplementation, you can have breast tenderness, periods. Okay, I'm gonna go to Instagram because I haven't been giving you guys love. What do I think about colostrum in a Hashi patient? You know, so here's the thing. I'm out. I'm still. The jury's still out. So I used to recommend colostrum with my patients, like, back in 2011, 2012. I never noticed a difference. That was obviously long before armra. Never noticed a difference with them. Never noticed a difference with it myself. So I quit for, obviously, like, a decade. And now I was trying to experiment with it myself. I usually try things myself before I recommend it to patients and haven't noticed any shifts. But I haven't been really diligent with it, so I can't really make too much of an opinion on it. Is it bad that I take 75 micrograms of Levo at age 24? No. Just because you're young doesn't mean you don't need it for sure. Taking LDN for about 10 weeks, still super inflamed. Other suggestions? Yes, you could do glutathione, you could do S acetylglutathione. You could do liposomal glutathione, you could do intermittent fasting. For me, I could not survive in my actual life without intermittent fasting. I would be so inflamed that I would be too tired to work in mom every day. And then obviously the most potent anti inflammatory agent that I have ever seen in my actual Life is a GLP1. The new class of weight loss medications. Semaglutide, Ozempic, Mounjaro, Zepbound, Tirzepatide. The most potent anti inflammatory agent I've ever seen. Thanks for joining me this morning guys. In my opinion, would a free T3 of 2.5 below. Absolutely. A free T3 of 2.5 is what I call pajama town. Not really wanting to get out of sweatpants. T3 needs to sit between about 3.6 and 4.2 for most of your day. Which means if you're checking it at your peak, if you're on a T3 based med, you need to check it's going to peak higher than that. Okay, y', all, I like need my glasses here. My doctor hubby just started me on a small dose of testosterone and already seeing better skin. Good for you. Libido, physical stamina, ability to exercise, ability to recover from exercise, all of those things. How do I feel about iodine and selenium? Selenium. So yes, iodine's a. I'm very careful with iodine and people with autoimmune issues because it can worsen them. It can worsen Hashimoto's. So if I recommend iodine, it's a small amount. I do not live in the camp of high dose iodine. How is estrogen dominance corrected? I'm so irritable and awful to my husband sometimes. So honestly. Right, write this down guys. So there's something you can do over the counter. It's a little tricky. I want you to think about estrogen dominance as we need. Thank you for the hearts, guys. We need to fix the root cause of it, right? And estrogen dominance can come from two little. I want you to think about it as an imbalance of estrogen and progesterone. Think about it like a scale, right? You can get it from too heavy estrogen compared to progesterone. You can get it from too light progesterone compared to estrogen like progesterone deficiency. Thank you for the hearts, TikTok. Or you can get it from both. You have to fix the cause. So if the cause is low progesterone, you have to Add progesterone. I usually honestly recommend doing that by an oral compounded form of progesterone. This is very different than birth control. Excuse my very messy vibrating plate in the back. There's like my bra back there. I should probably go move that. Right? I'll just scoot over. There we go. So you can add compounded progesterone. This is natural supplementation. This is not overriding your period. You can also reduce estrogen if you have too much estrogen. Usually that is specifically like the breast tenderness peas. Cramping at ovulation, spotting at ovulation. For that you can take over the counter. Dim. Dim is an enzyme that helps to break down and metabolize out estrogen. My very, very, very favorite one in the world that I think works the best is called Dimensions 3. It's by a brand called Zymogen with an X. But you can also get dim elsewhere too. And that will help you just metabolize out estrogen more efficiently, which is life changing. Like it's freaking life changing. Guys, Can you reverse Hashimoto's 100%. I still recommend progesterone for women with a full hysterectomy. I consider it an old wives tale that you guys don't need progesterone. You desperately do. I can only imagine if you don't have it, you're anxious, you don't sleep and you're irritable. There was another question and I already forgot. What was it? Oh no. Oh yeah. Can you reverse Hashimoto's? I used to have Hashimoto's. I haven't had it in well over a decade. I used to have a giant goiter. Like if you guys know what a goiter is, it's that giant like fat looking pad on your neck. It's not fat at all, it's inflammation. But people think they just like gain weight in their neck and that's not it. You can absolutely reverse it. You can get into remission, you can reduce your antibodies and not necessarily completely reverse your Hashimoto's and still get tremendous benefits. What lab numbers criteria do I use when I'm dosing afternoon thyroid beds? So most people need almost or as much afternoon thyroid medication as they take in the morning. So I usually test off morning because it's your natural T3 peaks highest in the morning and then it so underneath your medication and then it kind of lowers as the day goes on. So I always want to know like, hey, what is people's highest actual threshold of T3? They're getting at throughout the day and so I test in the morning and I put them on afternoon dosing to match their morning peak. Age 60 Post Postmenopausal hypo on armor on GLP1 what to do for hair shedding so you guys, the hair shedding from GLP1s comes from micronutrient depletion. So you need to be sure you're getting enough micro macronutrients protein. Thank you for the hearts TikTok. Y' all are the best. Y' all are sweet to me. And micro macronutrients. I would take neutrophil if you're shedding I would consider doing a micro dose of minoxidil like 2.5 milligrams. That's oral minoxidil. Minoxidil is Rogaine which you can absolutely use topically, but you can use it orally to protect your hair from shedding, to increase blood flow deliverability to your hair follicles, nutrient deliverability and yeah some I have like so many things for hair loss. I love collagen, the pink one from vital proteins that has the type of collagen for hair, skin, nails, red light therapy, scalp stimulator, like little scalp massagers, all of those types of things. And I would totally consider doing topical minoxidil and oral as well. Thoughts on breast implants? Already having Hashimoto's so I was actually talking with one of my patients about this yesterday. It's hard, guys. It's tricky. So do I think breast implant illness is real? Oh my gosh, of course I do. Do I think that a lot of people can get breast implants and be resilient to them? I kind of do too. And if you know that you struggle with autoimmune diseases, multiple autoimmune diseases especially, you know, it's. It's something to consider when making that decision. But it's such a personal decision. It's like how uncomfortable are you in your skin? How does that weigh against the risk for potentially worsening autoimmune disease? Can you check your antibodies before you if you decide to get them, and then check them frequently during so you can see how your body's responding. But just because your antibodies don't increase doesn't mean they're not making you inflamed. I would certainly, you know, do your research into types of breast implants because some are more heavily reactive than others. Silicone ow tends to be more reactive than saline, but even saline covers often have silicone in them. Lotus naltrexone can act as an anti inflammatory for autoimmune conditions. Yes. I didn't know if that was a question, but absolutely they can directly reduce antibodies. I can't really talk about shin splints and ankle pain related to hypothyroid. I mean it could be, but it's definitely not a common symptom. Could be associated with Hashimoto's. All right, let me look at Insta. Insta makes this so hard because they don't screen out comments. Let me see if I can like swipe over or something. Nope. So they just show me everyone that's joining and it's like 1 million people joining and then a comment. And then 1 million people joining and then a comment paused due to connection. It's not fun. Instagram. Okay, T3 is 3.0. Everything else is in range. People generally are symptomatic if their T3 is 3.0. T3 is yalls most important hormone, guys. So if it's low, if it's subpar, you're going to feel that. I've been seeing more about SEOs gummies. Is it good for thyroid health? I think the jury is still out on that. In fact, I did see an. An article, not like a scientific article, but like a General article about SEOs being bad for thyroid. I don't know though. Yeah, I, I can't really speak to it with any certainty, so I don't want to, don't want to lie to you guys. Are there any side effects to dim? If you take too much dim for too long, you can lower your estrogen too much. Thoughts on Cytomel? Love Cytomel. On Cytomel. Use it with patients every day. Love it. I think it's a great addition to levothyroxine testosterone supplementation with hypothyroidism. Is it okay? Absolutely. A lot of women with thyroid conditions need to supplement testosterone. What are the progesterone and estrogen ranges? So our hormones throughout our cycle are like this, right? They're crazy. Thank you for the hearts. You guys. Give me all the hearts. They're up and down. So we have to check hormones at a specific time of your cycle. Otherwise we do not know how to say what range they should be in because we don't know where they should be because that's not a specific time in your cycle where we can understand how to interpret your hormones. So if you have a period, the best time to check your hormones is the midway point between ovulation. Thank you for the hearts. And your next period. Oh, thanks for the fires. So to give you a little understanding of what that means, if your period is 28 days, if your cycle, excuse me, is 28 days, and you ovulate on day 14 and you start your next period on day 28, you'd want to get your hormone labs checked on day 21. If you ovulate at the right time, you start your next period on time, your progesterone is at its peak and your estrogen is at its midway peak. So during those times. What's going on with my eyelashes? Your progesterone should be between at least 6, 16. Really? Honestly, closer to 20, up to about 23, 24. Your estrogen should be 80 to 120. If your estrogen is above that, you're estrogen dominant from having too much estrogen. If your progesterone is below 16, your estrogen dominant from 2. Thanks for the hearts, guys. You're estrogen dominant from 2, little progesterone. Does that make sense? Do I take insurance? We do not take insurance. Actually, we spend way too much time with our patients to take insurance. If we did, for example, we spent an hour with our patients on our first appointment. If we took insurance, we would get paid between 34 and $65 for that hour and we would close our doors in one month because that is not realistic or sustainable. And that is why you guys are really unhappy with your care. Because your doctor is taught to see you in 8 minutes and you know what you can't solve in 8? To see you in 8. Empower your patients and educate them and teach them about their condition and give them the ability to make disempower your patients and educate them and teach them about their condition and give them the ability to make decisions about their care. None of those things can happen in 8 minutes. NP causing increased heart rate and hair loss. So usually that's because the person that's giving you NP does not know what they're doing. I'm sorry, but that's kind of the deal. Most people get NP once a day or prescribe NP once a day, which is wrong. In order to get enough T4 to balance your thyroid on NP, you need twice a day dosing. If you do it once a day, most people don't have enough T4 and they have too much T3 causing increased heart rate and then they crash and burn in the afternoon and they don't have thyroid function for 2/3 to 3/4 of their day because NP is short acting. So now you have no T3, no active hormone in the afternoon, evening, overnight, your T4 is too low, which is the thing that you need all day, every day to protect you from hair. And so now you're in this double deficit. So most people feel terrible at 4pm but they also need way more long term, stable hormones to protect their hair, their hormones, their metabolism, all the things. So you just, you know, desiccated thyroid can be great, guys. Like, it can be life changing. It gave me back my life. Desiccated thyroid is NP and armor at PISA. But 99.9% of clinicians do not know how to use it. They're afraid to use it appropriately. They under dose people, they don't appropriately dose people. And people get worse and they don't get better. And so it is so important that if you are having issues on a desiccated thyroid and that you find someone that with nuance knows what they're doing. Armor has helped me. So I don't understand this. That's fantastic. You know, like armor's amazing. And some people, they get freaking lucky and they can end up with a clinician that can kind of just try to do the right thing and they can feel good. And those people, God bless them, go buy a lottery ticket. It's kind of like the people who feel good on levothyroxine. It's like, go to Vegas. Like go hedge some bets somewhere because you are so darn lucky. I'm from the Philippines. Is dry skin normal for hypothyroidism? Hi. In the Philippines? Yes. Dry skin, dry hair, hair shedding, nails, breaking, all of those things foreign. So every Friday on Tick Tock, I'm trying to go live at 9am Central. I've set my schedule on Tick Tock to say Thursdays. Don't know how that happened, but I did it. So I'm gonna fix that today. But Tick Tock, if y' all want to join me on Fridays for lives, we can hang out and ask questions. Instagram. I'm going to try to do it when I have two phones that I can use, which is generally about every other week. I have my daughter's phone here that I can steal and borrow to do it. But if you're not on Tik Tok, follow me on Tik Tok. It's fun. Any recommendations for fighting fatigue while I'm on semaglutide? It's all I want to do is sleep. Absolutely. About 20% of our patients in our program, up to 30%, feel fatigued. One you want to be on the least amount of medication possible because that will help you with fatigue. But I recommend two supplements for my people on GLP1s with fatigue. One is Adrenal. Adrenal is life changing. If y' all haven't heard me talk about it, I talk about it all the time. The dosing on adrenal is a little tricky. You have to kind of start slow and increase up. Obviously check with your doctor. This is not medical advice. But I have people start with one in the morning, one with lunch, and then slowly increase up to three and three. And they do so based on how they feel three to five hours after they take it. Mitochondrial supports easier dosing. I love and I think I put this in my Amazon storefront. It's called Mito nrg. I take this every day. In general, I love it. I have some right here. Mido Energy by Designs for Health. One to two in the morning, one to two with lunch. God, I love it. I changed my life because I have terrible mitochondrial function. Okay, let me go back to tick tock for a second. I'm on armor thyroid now. I'm up to 180 per day, TSH and range, but still not feeling good. Antibodies are bad. Yeah, I mean I would have to have so much more information. Madison, that's a lot of armor, especially if you're taking it at one time. It's honestly too much for people even post thyroidectomy to take at one time. So it's probably causing issues, but I just don't have enough information to speak to it. Is Levo and Synthroid the same medication? Basically, yeah. I was just starting to NP2 grains, but only once a day. I've noticed I'm so tired. I'm sure you notice you're tired too. Like in the afternoon especially. It's always the hardest time. And honestly y', all, I kind of prefer armor to NP in general. I find 100% of my patients just feel better on it. It's more expensive. Yeah, but every patient that's come off of armor and gone on NP because of the money situation, they've 100% of them have come back and been like, you know what? I think I'm just gonna pay extra for armor cuz I felt so much better on it, so might be worth trying to switch. And always if you're on desiccated thyroid armor or MP, most people feel bad at 4pm if they're on one city dosing. So just an FYI, My thyroid was removed at the end of April. My hair shedding has been crazy. Someone just said, I'm a patient of modern thyroid, and I switch from NP to armour and feel so much better. Thanks for that. Yeah, I, I, you know, it's hard. I, I have to broach that topic delicately, but I also kind of feel like you guys deserve to know that it's worth trying. Okay, let's see. Okay. So to the person who had their thyroid removed at the end of April, time is a very important thing for you right now. So most people with a thyroid problem who have not had a thyroidectomy can get their thyroid fixed now or in 30 years, and you know what? The outcome's kind of the same. They can get their life back.
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