Short diarized transcript excerpt of a conversation (YouTube) about senescent skin cells. Speakers state that accumulated senescent cells secrete inflammatory factors, driving collagen breakdown, loss of skin elasticity, and other aging-related skin changes.
Got.
It. And those senescent.
Cells, when they accumulate. Yeah. Start to secrete inflammation on their own. That then leads to collagen breakdown. Other like just loss of its skin elasticity. Tell me. Yeah, you tell us.
Collagen breakdown, which loss of elasticity on the skin, thinning of the epidermal layer, the breakage of the skin barrier which leads to less hydration of your skin, reduce also the cell turnover because it also impacted the stem cells on your skin. So your skin also is more. Has more dullness. The wound healing process starts to become slower. So the senescent cells is one of the root causes of why everything of this is getting disturbed. Because this inflammation that they secrete create an environment that is unhealthy. It's like leading to damage. Yeah. And is it using the healthy cells to also become damaged as well? So it's kind of a cascade. The more senescent cells you're kind of induced and you are accelerating this aging process.