McCall McPhersonFounder, Modern Thyroid Clinic.

Unlocking Health: The Impact of Testosterone on Cardiovascular Disease

6 Feb 2025 · 1 min

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1:03

A short excerpt from a YouTube conversation (host McCall McPherson and Speaker B) discussing research linking low testosterone to increased risk of adverse health outcomes. McPherson states low testosterone is associated with a 24% increased risk of cardiovascular disease; Speaker B references large studies (including VA cohorts of ~150,000) reporting associations with all-cause mortality, cardiovascular outcomes, reduced bone density, and increased tau protein accumulation (implicated in Alzheimer’s/dementia). Both note these findings suggest potential benefits from optimizing testosterone but emphasize that clinical indications and further study are needed.

Chapters

In terms of cardiovascular disease, if you have low testosterone, you're at a 24% increased risk of cardiovascular disease. So what does that mean in reverse? It means if we can restore your levels to optimal, likely you're gonna see a reduction in cardiovascular disease risk. It's so great to have access to that more up to date progressive real information.
I think the stats are staggering, right? You mentioned low testosterone and cardiovascular risk and that that percentage and there have been again studies that have looked at mass populations. I'm Talking about even VA studies with 150,000 people looking at all cause mortality. You're looking at cardiovascular risk, bone density or even tau protein accumulation. People, Alzheimer's and dementia are a huge topic today. And you again there's data that shows having testosterone deficiency is implicated in increase of these proteins. So again like you're saying by function of that and disclaimer, these are not indications today. And testosterone and Kaiser track still have to be studied for them. But you can see the relationship and where the research needs to go.