Why you still have thyroid symptoms

3 Jan 2024 · 4 min
3:55

A short YouTube talk by McCall McPherson (founder, Modern Thyroid Clinic) arguing that persistent thyroid symptoms (fatigue, brain fog, weight gain) despite T4-only therapy are commonly caused by a "conversion disorder"—impaired conversion of inactive T4 to active T3. She lists factors that suppress conversion (inflammation, low micronutrients or protein, calorie restriction, chronic stress/poor sleep, pregnancy) and recommends low-inflammatory, nutrient-dense diets, sufficient calories/protein, stress reduction and sleep improvement to support conversion. When lifestyle measures are insufficient, she advises clinicians to consider prescribing T3-containing medications (liothyronine/Cytomel, Armour) to restore active hormone balance and improve symptoms.

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