McCall McPhersonFounder, Modern Thyroid Clinic.

Your Gut Might Be Blocking Your Hormones! #shorts

21 Apr 2026 · 0 min

Watch on YouTube

0:10

In this YouTube Short, McCall McPherson and a guest discuss how the gut and hormones influence each other in a bidirectional loop. They explain that gut inflammation and microbiome disruption can trigger higher cortisol and stress, while elevated stress hormones further damage the gut microbiome. This vicious cycle leads to subtle but common symptoms such as acid reflux, bloating, random food cravings, and severe constipation. The conversation highlights that many people unknowingly harm their gut over time, which then impairs hormone production, reinforcing the cycle of inflammation and hormonal imbalance.

as I researched the gut more and more, I just realized, you know, the gut is where all disease processes begin because our gut is what drives so much inflammation.
Do your hormones impact your gut? Does your gut impact your hormones? Is this a bidirectional relationship?
And so your hormones can affect your gut, but your gut affects your hormones. And so then we get into this big vicious cycle, higher cortisol levels, stress, et cetera, that is affecting our gut. And so a lot of us end up kind of just slowly over time destroying our gut microbiome, not realizing it, but we do. And we end up with symptoms like acid reflux or bloating after we eat, or we have random food cravings and we just think, oh, that's part of life, right? But it's really not. Or we're severely constipated. And so these are slow symptoms that, hey, I'm doing something that maybe is affecting my gut and my microbiome, right? And so as we disrupt our microbiome, then our microbiome also will disrupt our hormone production.