As you age, your gut produces more phenylacetic acid, a molecule that damages blood vessel linings and increases heart attack risk. Better sleep and possibly apple cider vinegar may help reduce the damage.
Chapters
A molecule made by your gut could be harming your heart. It's called phenylacetic acid, and as we get older, as we age, our microbiome shifts to make more phenylacetic acid. Why is that a problem? Because phenylacetic acid causes mitochondrial dysfunction, oxidative stress, and inflammation in the cells lining your blood vessels, endothelial cells. And this chain reaction increases your risk for heart disease. In fact, higher levels of this molecule, PAA, phenylacetic acid are linked to major adverse cardiovascular events in humans. But the good news is getting quality sleep and even apple cider vinegar may help reduce the damage. For more science and more nuance, check out the notes below.