Nick NorwitzMD PhD, Oxford-Harvard | Metabolic Health Educator | “Stay Curious”

The Hidden Cause of IBS

13 Nov 2025 · 1 min

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In this video, Nick Norwitz introduces the growing prevalence of irritable bowel syndrome (IBS) and related functional gut disorders, emphasizing that most sufferers experience bloating, constipation, or diarrhea. He then presents recent scientific findings that identify a specific pool of gut‑derived serotonin, produced by particular gut bacteria, as a key driver of IBS symptoms. While he cautions that this is not a guaranteed cure, he argues that the data could fundamentally shift how clinicians approach gut health, moving beyond generic advice such as “just eat more fiber” toward microbiome‑targeted strategies.

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Have you struggled with bloating, constipation, or diarrhea? If you have, congrats, you're in the majority. Irritable bowel syndrome and other functional gut disorders aren't rare anymore. They're becoming the norm. But what actually causes IBS? New research points to a surprising culprit and a potential cure: a specific pool of the hormone serotonin in your gut made by specific gut bacteria. I'm not promising a silver bullet, but in a medical world constipated with clichés like "just eat more fiber," these kind of data could shift the entire way We treat gut health.