Jaiwant Rangi, MD, FACEEndocrinologist | Founder, Lower The Dose® | Speaker

Decoding the Subtype: Tailoring Treatment for Autoimmune Deficiencies

17 Jul 2026 · 1 min

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Your autoimmune disease subtype shapes which medications work and what complications to expect. Ask your doctor to identify yours. For severe cases, start insulin right away, typically basal insulin like glargine or degludec plus rapid-acting insulin at meals.

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Knowing your subtype can make a big difference in the lab results that we get, in the medications that we choose, and in regards to the expected complications over time. So there's a lot of effect of knowing the subtype. So knowing your subtype can matter, but I'm not sure if everyone can find their subtype in their practices, but they should try to encourage having that discussion with their doctor. In regards to severe autoimmune deficient, the medications that we want to do is you want to start insulin earlier on. You don't want We don't want to wait for too long to start them on medication. Usually we start with basal insulin like Glargine or Degludec, and plus they will need short-acting insulin or rapid-acting insulin with meals. Metformin can be added but isn't primary.