Jaiwant Rangi, MD, FACEEndocrinologist | Founder, Lower The Dose® | Speaker

Smarter Diabetes Care: Trading Old Co-pays for Modern Organ Protection

1 Aug 2026 · 1 min

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Dr. Jaiwant Rangi argues that older diabetes drugs like sulfonylureas lack heart and kidney protection, causing weight gain and low blood sugar. When newer medications cost too much out of pocket, doctors should help patients drop the old drug and switch, since the newer class protects organs beyond just lowering glucose.

Chapters

Somebody's blood sugar is not under control, and I end up adding one of these new classes of medications, and the patient will say, I have such a big copay and I can't afford it. So I have to educate them that let's stop the other medication because the other one you're paying so much copay and it's not doing any cardio protection. It's only lowering the blood sugar. So it's important to understand that the older sulfonylureas, they squeeze the pancreas to make more insulin and secrete more insulin. They lower the sugar, but they can cause low blood sugars and some weight gain. So both the things that we don't desire, and they do not any organ protection of newer classes.