Jaiwant Rangi, MD, FACEEndocrinologist | Founder, Lower The Dose® | Speaker

The Clock Is Ticking Long Before the Diagnosis

29 May 2026 · 1 min

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0:32

Dr. Jaiwant Rangi explains that diabetes develops over years, not suddenly. Abnormalities in glucose and metabolism show up as early as 13 years before diagnosis, with the sharpest changes in the 4-5 years right before. Early screening catches it long before symptoms appear.

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We wait for the disease to happen. We don't do early diagnosis and we don't use the markers in the beginning stage. We know that it takes years to develop diabetes. Diabetes doesn't just show up overnight. In major long-term study, the changes in glucose trajectory and the metabolic function were detectable up to 13 years before the diagnosis. And the steepest rise or the change that we see happens in the previous 4 to 5 years or so, or the few years right before the diabetes diagnosis happens.

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