Jaiwant Rangi, MD, FACEEndocrinologist | Founder, Lower The Dose® | Speaker

The Crucial Window for Diabetes Care

5 Aug 2026 · 1 min

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After ten years with type 2 diabetes, the pancreatic cells that make insulin have mostly died or stopped working. Remission becomes impossible at this stage, though researchers are exploring whether lost cells can be regenerated or preserved to restore insulin production.

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After 10 years, when you are in the third window, like you said, which we have the silent window when the reversal is half possible, then you have remission and protection, and the last one is protection only, which is 10+ years of diabetes. That's when the beta cells, or the cells that make your insulin, have undergone more permanent changes. Most of them have either died or they have become dysfunctional, you know, beyond recovery. Some of them you can bring it back. Nowadays, there are studies to understand, can we have beta cells that we can bring them back, or can we do anything to Preserve them.