Jaiwant Rangi, MD, FACEEndocrinologist | Founder, Lower The Dose® | Speaker

Vital Indicators of Metabolic Decline

10 Jun 2026 · 0 min

Watch on YouTube

0:25

In this excerpt, Dr. Jaiwant Rangi explains key laboratory markers that signal early metabolic decline. He outlines the hemoglobin A1c ranges used to diagnose prediabetes (5.7–6.5%) and diabetes (>6.5%). He also notes that elevated triglycerides and low HDL cholesterol are common lipid abnormalities that serve as early warning signs of metabolic dysfunction. The speaker emphasizes that these lab changes are not random complaints but important indicators for clinicians and patients to monitor.

They can also have the hemoglobin A1c, the number that we use to diagnose as prediabetes, if it is between 5.7 to 6.5, and if it's more than 6.5, we diagnose that diabetes. So that can start trending up, and we also notice some people can have elevated triglycerides or low HDL. Those are types of cholesterol that we monitor. These are not random complaints. They're early metabolic warning signs that we see quite common.