The Achieve Podcast - Leo Castaneda (Think AES)

15 Apr 2026 · 23 min
22:31

In this episode of the Achieve Podcast, host Taylor Baker interviews Leo Castaneda, CEO of Think AES, about his unconventional rise from a warehouse clerk in New Jersey to leading a global biotech engineering firm. Leo recounts his self‑taught path through hazardous‑waste work at Bristol‑Myers Squibb, automation engineering at Genentech, and the founding of Think AES, now a 300‑engineer organization with 14 offices across four continents. He explains that massive capital investment in biotech fuels the company’s growth, and that Think AES differentiates itself by acting as a partner rather than a traditional service provider—leveraging deep process, automation, and equipment expertise to design facilities with minimal client direction. Leo discusses the biggest operational hurdles: managing a widely dispersed team, scaling without venture‑capital backing, and overcoming limited brand recognition when pursuing large contracts. Marketing and lead generation are identified as ongoing challenges, with the firm relying on personal networks and partnership messaging. The conversation turns to the role of AI and automation in accelerating documentation and recipe design, and Leo shares excitement about launching an internal AES Biologics CMO to showcase the company’s end‑to‑end facility capabilities. He reflects on key lessons—particularly the importance of understanding finance and the banking system early on—and offers advice to aspiring entrepreneurs: work hard, hustle, and “knock on doors” to create opportunities. The episode closes with Leo emphasizing the need for better connection between biotech CEOs with capital and service providers like Think AES.

Chapters

More from Taylor

15:57
youtube.com

Jacoba Gundle (Mindful Proteins)

3w ago
25:58
youtube.com

The Achieve Podcast - Ramesh Swamy (Halifax West)

3w ago
19:01
youtube.com

The Achieve Podcast - Santosh Kanse (Go Source)

3w ago
28:52
youtube.com

The Achieve Podcast - Kutral Veerabadran (The Second Whistle)

1mo ago
23:15
youtube.com

The Achieve Podcast - Gary de Rodriguez (Peopleistic)

2mo ago
21:30
youtube.com

The Achieve Podcast - Steve Sapourn (The Neuro's Journey)

2mo ago
21:13
youtube.com

The Achieve Podcast - Zachary Hedges (Customer Model AI)

3mo ago
youtube.com

The Achieve Podcast - Paul Adams (Sound Financial Group)

4mo ago
youtube.com

The Achieve Podcast - John Morgan (Pelagic)

4mo ago
youtube.com

The Achieve Podcast - Sanjay Bhatia (Runday.ai)

4mo ago
youtube.com

The Achieve Podcast - Brad Hawkins (Infinite Protection)

4mo ago
See all content