Aaron Hartman, MD explains that proton pump inhibitors block the same pumps mitochondria use to make energy, potentially harming cells. Long-term PPI use is linked to dysbiosis, SIBO, fungal overgrowth, cardiovascular disease, kidney disease, dementia, and B vitamin deficiencies, though they work well short-term for ulcers.
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Proton pumps actually are what on your mitochondria for making energy. So proton pump inhibitors can also be toxic to your mitochondria. So in some people, the proton pump inhibitors can actually have be super detrimental. They are harmful because they increase your risk for getting dysbiosis. They increase your risk for SIBO and sifo, which is small intestinal fungal overgrowth, which is another bad thing, and yeast infections. If you're a female with yeast infections or weird like vaginal infections or vaginal overgrowth or weird smells BV kind of stuff, the PPIS can set you up for that as well. And it can also increase your risk for cardiovascular disease, renal disease, dementia, nutrient deficiencies, B vitamin deficiencies. They're amazing medications, short term for preventing ulcers, but long term. I agree with this question. You got to find something else.