Aaron Hartman, MDFunctional Medicine Specialist | Clinical Researcher

Dr

14 Aug 2024 · 1 min

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0:38

Short clip from a YouTube lecture (speaker Aaron Hartman, MD) discussing how pro-clotting genetic traits were advantageous in early human environments with frequent trauma, but became deleterious later in life (e.g., contributing to atherosclerosis). The speaker mentions loss of the 'LP gene' as a possible recent change and frames clotting propensity as historically adaptive then maladaptive.

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At one time in our existence, it was good to have a lot of clotting factors because trauma was so prevalent in the early human existence. Falling down, getting bit, scraping yourself, people were bleeding all day long. So those who had a propensity to rapid clotting had survival. Nobody was worrying about atherosclerosis 40 years later. So having a clotting factor was probably good at a certain point in our revolution, but. But at a certain point it became deleterious. So all of a sudden there's been a loss of the LP gene, and so that's the core. Who really knows, you know?