Functional Medicine: What is it and why does it matter?

Podcast episode (Richmond Integrative and Functional Medicine) in which Aaron Hartman, MD, recounts his personal journey into integrative and functional medicine driven by experiences with his adopted children’s complex medical needs. He describes rejecting some recommended invasive interventions, exploring nutrition, gene-expression approaches, and attending integrative medicine conferences (Academy of Integrated Holistic Medicine, Institute for Functional Medicine). Hartman explains core principles of functional medicine: systems-biology thinking (assimilation, defense/repair, biotransformation, energy, transportation, communication, structural integrity), the functional medicine matrix/tree model (symptoms→organ systems→functional nodes→antecedents/triggers/mediators→lifestyle roots), and emphasis on modifiable lifestyle factors (sleep, exercise, nutrition, stress, relationships). He positions integrative/functional medicine as evidence-informed, patient-centered, and complementary to conventional acute care, and previews a follow-up episode on diet and lifestyle.
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Welcome to Foundations of Functional Medicine with Erin Hartman, MD. This is a podcast of Richmond Integrative and Functional Medicine. This podcast seeks to motivate individuals to reclaim their health through education, encouragement and empowerment by reviewing the basic tenets of functional and integrative medicine as well as discussing new advances shaping the future of healthcare in our country. To learn more about us and keep up to date on other important health related topics, Visit us at www.richmondfunctionalmedicine.com. the following discussion is for educational purposes only and is not intended to diagnose or treat any disease or disease process. You should always discuss any medical treatments or interventions as well as changes in your health with your personal physician.
I often get asked to explain what integrative and functional medicine are, especially in light of the newfound popularity. But before I do this, I'd actually like to go a little bit into my own personal professional journey and how I got into this field of study. And it all starts with my family. When my wife and I were married in 2004, she was a practicing pediatric occupational therapist and she exclusively worked with kids with special needs. Her entire caseload consisted entirely of these super rare cases of children with things I'd never heard of. I'd never heard of them in medical school and never heard of them in my residency, and it just was amazing to me that she would have case after case after case of a child with a diagnosis, and I'd never heard of most of them. They were pretty involved cases as well. This was intensified when we adopted our first daughter, Anna. Anna was actually one of my wife's patients that she started taking care of when she first got out of the hospital. She kind of fell in love with my daughter and when my daughter's foster home was closing, she needed a place and so my wife asked me if we'd be willing to open our home to this little girl and I said yes. And so we started to foster Anna. It was hard. A child with special needs is a lot of work, but we were up for the challenge. When Anna was about 14 months old, her pediatric gastroenterologist recommended a feeding tube. What this is is a little tube they put in the child's stomach for the express purpose of pouring in formula so that the child can grow. The reason for this was that Anna was less than the fifth percentile on a growth chart and and hadn't changed in a couple of months. And her GI specialist thought that we gotta do something about this, so let's put this feeding tube in. It didn't feel right to me. And neither did it feel right to my wife. We talked about this and my wife told me how having a feeding tube in can affect the speech development on a child. And that was a big deal, especially since my daughter wasn't talking at this point in time. It could also affect crawling, walking, motor development, and again, really, really big deal, because at this point in my time, my daughter couldn't even sit up on her own. You sit up and she would just fall. Right. So putting something in that's going to affect her neurological development just seemed like a terrible idea to me. So we gently opted out of that. The pediatric physician did not take that very kindly. She talked with a nurse, was considering reporting us to child protective services. And so my wife talked with a nurse. She actually had a really, really good relationship with a nurse because my wife had been working with multiple kids with special needs and they actually knew each other from all these other children and nothing came of it. But this was the first time in my professional career where I directly went against doctor's orders and did something totally opposite from what was recommended by the specialist. This healthy questioning of medical authority, so to speak, was strengthened when about six months later, my wife found a pediatric growth chart for kids with special needs. And my daughter was right in the middle. She was at the 50th percentile. So my wife found this chart. Yet the specialist had no idea this chart existed. And that was another mind blower for me. How was this possible? That someone was recommending a potentially life changing, life altering, surgical procedure that my daughter actually didn't even need? The scenario, unfortunately, was to play out multiple times over the next several years. The following year, an ophthalmologist recommended eye surgery for my daughter because she has lazy eyes and they kind of move a little bit, very randomly actually, and they recommend this surgical procedure to help.
Quote, unquote, with her vision.
The reality was, is that from my research I learned that it actually probably wouldn't help her vision at all. It was largely cosmetic. So my wife and I looked around for a second opinion. We found a more seasoned pediatric eye doctor who had been doing this for 30 years. And they agree with us that the surgery itself for her would not improve her vision. It would help cosmetically, but as she developed, she might develop the eye problem again and it wouldn't really have any long lasting value to her. So we opted out of that surgical procedure and that was strike two for us. Unfortunately, that continued to happen every year too, where someone recommend a surgical procedure for us. We'd research it, try something else, and eventually we'd not have to do that procedure. While all this was going on, my wife had started looking into diet, nutrition, lifestyle changes for our family. She'd started changing out certain foods and putting other foods in, getting rid of certain chemicals we had in her house for cleaning, et cetera. I was, you know, just along for the ride. I wasn't bucked too much. I wasn't really into it that much, mainly because I grew up spraying everything. We had a little orchard in our backyard as a child and my dad would use seven and all kinds of bug sprays on our peach trees and apple trees. Never hurt me, but I'm going to buck my wife. And so while this is going on, our family's lifestyle is slowly changing. During the same time, I actually stumbled across some of the work of Dr. Amy Yasko, who is a specialist that works with kids with autism. What she does is she looks at the kids genes, tells what gene defects they have, and then with nutrition and supplements will alter the gene expression. Her work is with autistic kids. My thinking was, could this help my daughter with another neurological issue, cerebral palsy. So I spent six months researching this, learning about gene expression, how nutritional things can change gene expression, and then start implementing this stuff with my daughter. Another thing that really inspired me to go down this pathway was this was the first time I actually found out there might be something alternative I could offer for my daughter that actually might help her. At this point in time, she was 4 years old and getting a little older. There's a very small neurological window where you can have big impacts on a child. And so the fire was kind of lit underneath me, so to speak, to really look into this. And I started to develop a passion for trying to find are there other things that actually might help my daughter. In 2011, I signed up for an integrative medicine conference in Florida with the Academy of Integrated Holistic Medicine. I'd gotten their flyers before and just kind of put them in the pile with all the other flyers. I wasn't really interested in it before because, you know, you got to take a week off of work and you take vacation time and I wasn't really interested in that. But at this point in time, my life, I determined this was probably going to be a good investment. Let me just go on, go down to Florida and see what's going on, see what I can learn down there. And the conference to me was almost like going to medical school all over again. I was singing at conferences, listening to things for six to eight hours a day of things I'd never heard of before, listening to Dr. Gabby, who wrote the Textbook of Nutritional Medicine, or Dr. Pizorno, who wrote the textbook of natural medicine, and just hearing things that seemed mind blowing to me in a room with 700 other physicians from across the country. The other thing that was astounding to me, that there's this room of 700 other physicians who some had practiced this kind of medicine for decades, and I'd never heard of it before, either in medical school or in graduate school. This shocked me. I was hooked and I just had to learn more. At the same time, we are adopting our second and our third child, each with their own unique health issues. When we got my son at 6 months of age, he had really bad asthma and eczema. His asthma was so bad, my wife would literally sleep with him on her chest at night because she was scared he'd stop breathing in the middle of the night and she had to be there. His eczema was so bad that he would scratch at his skin and give himself little cuts and ulcers on his skin from scratching. My other daughter had her own developmental issues, yet all of them have had major, major gains. My son no longer has asthma, he no longer has eczema, and he only has occasional allergies when the weather changes. My oldest daughter, Anna, now walks with forearm crutches. At the age of 13, she's had no surgical procedures, even though she's had about six recommended to her. And that's quite a big feat for a child with cerebral palsy to make the 13 with no surgical procedures. None of my kids have had cavities, and between the three of them, they've only had anabox once. These would be considered great feats for a typical family. For a family of kids with special needs, these are extraordinary. While this is going on, I also fell across another piece of information and discovered the Institute for functional medicine in 2012, I dove right in. This was a huge accelerate for my learning process. At each of the training modules, I'd be in a group of professionals around the country, learning from doctors from Harvard, Hopkins, University of Michigan, all these really kind of big name kind of places that are obviously very intellectual, hearing about things I'd never heard of before. How is it that there's so many people from so many prestigious institutions around the country that are saying things I'd never even heard of before? At each one of these modules, my fire be lit and get fed and grow even more. I learned about pulsed electromagnetic field therapy at one of the conferences, which is a type of magnetic therapy. Think about it as a pulsing magnetic, so to speak. Sounds kind of weird, but they've been using this technology in Russia since the 60s, in Poland as well as other eastern European countries for decades. Even horse trainers here in America will use it for their high end racehorses to help treat their aches and pains and help them heal quicker. Yet I never heard of it for use in humans, even though now there's actually a device that's FDA approved to treat depression that is this exact same type of technology. I also learned about laser light therapy and then dove into that and studied that for about six months. That's an interesting technology that they're using in Canada right now to treat traumatic brain injury patients. Again, something I'd never heard of before. That one part of the world they're using a fair amount of. Each time I come across a new topic like this and dive in. It was another Alice in Wonderland kind of thing where I got somewhere, I'm like, wow, this world truly in color. And I would learn new things, incorporate them into my family, into my daughter's care, and it would kind of automatically bleed out into patient care. This was for me, a nine year process. As I was learning these concepts and expanding my own academic and professional training, I would start to offer them to patients who seem interested in these kind of therapies. Patients whose diabetes hadn't gotten really better or pain hadn't gotten better. One of the patients I'm referring to had fibromyalgia for years, had seen multiple specialists in the Richmond area and was just on a lot of pain medications and didn't feel any better. One of the conferences we had talked about peripheral electrical stimulation with a device called Quell, which you can buy Bed Bath and Beyond. So it's gotta be legit, right? So we, we used it with her and three months later, 80% of her pain was, was gone. I was flabbergasted. This was absolutely amazing. It's something I learned about at a conference and no one in my local area was actually using this. I continued to work with willing patients, but it was difficult. It's really hard to apply this degree of complexity to someone in the office when you only have 12 minutes of time. So in 2016, after finishing my certification in functional medicine, I decided to try another experiment. Let's see if anybody in Richmond actually.
Would be interested in this kind of medicine full force.
So I built out a website, put up the shingle for Richmond Integrative and Functional Medicine and launched that in January 1st of 2017. It's been nothing less of astounding and amazing. The journey has been quite unique. I'm actually quite overwhelmed by the response from patients as well as the general public. One thing I've learned this whole process is there's a huge unmet need for.
This kind of medicine.
Individualized, personalized, yet grounded in the most up to date scientific literature. That's led me to the next phase of my patient centered educational career and I'm now starting this podcast. My first goal in this process is to create a two part series. Part one would focus on the foundations of functional medicine, which are also known as lifestyle medicine in the functional medicine world. This is the foundation for any personalized healthcare program. The next part of the series would be to dive into the nodes of the functional medicine matrix. These are the systems, the way we think about disease or disease processes in the functional medicine world and just to go through each one of those processes and explain them to people so they can understand how I think and how functional medicine practitioner thinks. Then depending on the response, I may continue to do the podcast, diving into more cutting edge type topics or simply just answering the most common patient questions or concerns. I'm not quite sure where this will go, but I'm excited to see where it leads.
So the next thing I'd like to talk about is what is integrative functional medicine? Many people ask me what this new thing is. They haven't quite heard of it. It sounds a little, a little strange, a little awkward. So I'd like to spend the next few minutes and just talk about what these things are. My personal understanding of it has actually morphed and changed and evolved as my practice has evolved from back in 2007 when I first joined Family Practice Associates to 2010 when I started Virginia Research center to 2016 when I started Richmond Integrative Functional Medicine. Each stage in my personal career has had this advancement in my knowledge base. So I'd like to start with integrative and functional medicine not by describing what they are, but describing what they're not. What integrative functional medicine is not. First and foremost, it's not unscientific. I hear this many times. People wonder, is this really true medicine?
It is.
It's actually the deepest and broadest kind of medicine. It's based on our knowledge of pathophysiology, different fields of medicine and science, like epigenetics, which is the expression of our genes, not just our genes or Nutrigenomics, which are how nutrition affects the expression of our genes, or metabolomics, which is how our metabolism affects our health. These are all integrated into the concepts of integrative and functional medicine. And there are many pioneers in this field of medicine, whether it's Dr. Mark Hyman at the Cleveland Clinic, Dr. Branson at the David Geffen School of Medicine at UCLA, who is probably one of the top Alzheimer's researchers in the country, was Dr. Fasciano at the Harvard School of Medicine. He's one of the top gut guys that actually discovered zonulin, if you ever heard of leaky gut. He is the physician who actually discovered the key to effects that he got. All these are thought leaders in the field that teach routinely in integrative functional medicine and are actually helping push the ball forward in this field of medicine. The other thing about this field of medicine, it's not specially driven. Integrative and functional medicine is not isolating the silos of your heart or silos of your lungs, or silos of your joints. It's a systems biology approach that looks at the root cause. What that means is you look at how does everything interact with everything else. Examples of how this can look would be someone with chronic fatigue syndrome, for example. When I initially did my training, chronic fatigue was thought to be a psychological issue. It wasn't thought to be a primary medical problem. Well, now we know that chronic fatigue syndrome and fibromyalgia actually lead to brain inflammation. So this systems biology approach would look at how does someone actually get fibromyalgia? Is it related to nutritional deficiencies, gene expressions, chronic infections, trauma, psychological issues, sleep disturbances, gut disturbances, and how all these can be looked at to then individualize care for a person. In this systems approach, every single solitary person is looked as a whole. It's a true type of holistic medicine. So it's not ultimately specially driven. So what is integrative in functional medicine? This definition is a pretty standard definition.
I'll try to walk through it a little bit.
But it's a unified and holistic, patient centered method methodology of delivering medical care with the goal of maximizing the individual's wellness. So it's unified and holistic. What does that mean? It means it looks at everything, the entire whole. It doesn't just look at the heart or the lungs. It looks at the person's history. It looks at the person's personal beliefs, their culture they've come from, how their culture affects their perception of disease. All these things can play into an individual's personal Health, it's patient centered, which ultimately means it always comes back to the patient. The not the physician looking at the patient, but the patient themselves and the delivering this medical care with the goal of maximizing individual's wellness. The goal is not maximizing therapies or maximizing utilities of procedures. It's the ultimate goals of individual's wellness, which means an individual has to be involved in the healthcare. It's not simply diagnosing and treating. The person has to be part of their own health care. And that's what makes integrative functional medicine unique. So when I say systems approach, what do I mean by systems approach? Systems approach again, it doesn't just look at organ systems, it looks at these biologic systems. This includes assimilation, how you eat food and incorporate nutrition into your body. Defense and repair is your immune system, how your immune system fights off infections, biotransformation and elimination.
This is how we detoxify our bodies.
Energy is the mitochondria, if anybody's heard of the mitochondria, the powerhouse, the cell. This system looks at how we actually make energy at the cellular level, but then feeds out to tissues, to organs, and then your entire body. Transportation. It's how do you get stuff around your body? How does your blood get stuff from point A to B? How does your blood get stuffed from point A to point B? How does your lymphatics move out toxins? Communication comes down to hormones. How do your hormones interlink with your heart and your lungs? How does your testosterone, estrogen and cortisol affect your sleep wake cycles? And ultimately the last one is structural integrity. This is joints, sinews, but also your interstitium. And interstitium is a fancy word for saying everything between cells. That's something that's often forgotten about in a traditional medical model. But yet most of us is actually interstitium. Most of our body is actually the stuff between cells, not the cells themselves. So these systems will affect someone's health. And so integrating these concepts can be really important for someone's health. The other thing is that integrating functional medicine takes the individual's unique microenvironment into play. So what is microenvironment? Microenvironment is that unique environment that's unique for you, for your time and your place in history, for your family, for your personal health history that include antecedents, which are things that led up to or pushed you towards whatever's going on in your health right now. Triggers may be things that push you over the edge and then mediators Are those things that keep your state of unhealth going forward. It's important not just to know what's going on, where you're at now, but what got you there, what pushed you there, and what maintains you there. And that's not included in a traditional way of looking at illness. The last part about integrative functional medicine is a strong emphasis on modifiable personal lifestyle factors. These form the foundation of functional medicine. And these modifiable personal lifestyle factors are sleep and relaxation, exercise and movement, nutrition, stress and relationships. If you're chronically stressed, it's going to be hard to fix your stomach because cortisol is going to keep on giving you leaky gut if you're not exercising routinely. It's amazing. Our bodies were designed or made to be out working eight to ten hours a day. And if you're sitting in front of a computer day long, it's gonna be really hard to help your body to heal. Especially when we're learning all this great information about exercise being the best antidepressant, one of the best things to control diabetes and hypertension, sleep. If you don't sleep at night, there's all kinds of things that can affect, including increasing your risk for certain cancers. So in functional and integrative medicine, this forms a foundation that we use to then inform the other layers or levels of looking at someone's health. This comprehensive diagnostic model is kind of looked like as a tree on my website. I actually did a blog post on this and I have a little tree diagram that describes the different levels of we look at things. The way to think about, if you can visualize this or see this diagram, the way we look at someone, it's first like a tree. The leaves at the very outside are symptoms someone has. They can have major symptoms, minor symptoms that can be suggestive of certain diseases, or you can have healthy signs or symptoms. You know, if you exercise and recover very quickly. The next level is actually the organ systems, which is our traditional way of looking things. That's your cardiology, which is the heart doctor, that's your neurology, which is the nerve or brain doctor, that's the pulmonologist or your lung doctor. After you get a sign or symptom. And you can think about things in the organ system that allows you to get diagnoses. But this model goes deeper, closer into the middle of the tree, you have the functional mass and matrix, which are those nodes I mentioned, the assimilation, the energy, transportation, communication. Next level below that, the antecedents, triggers and meteors. I mentioned these are the actual trunk of the tree. The whole tree is held up by these. If you don't have things that lead up to illness, things that push you over the edge with illness and keep you there, it doesn't happen. Same thing with health. You have to have antecedents that lead up to a healthy life, triggers that you keep on doing to maintain your healthy life, and the meteors that keep you there. But beneath all this, at the very bottom, the roots of this tree are your lifestyle, environmental factors. That's again, sleep, relaxation, nutrition, stress, relationships and exercise and movement. So when you look at a person from the functional medicine perspective, you're looking at this entire comprehensive diagnostic model.
Another way I like to think about.
Traditional medicine versus alternative medicine as in many way two sides of the same coin. Sometimes people refer to this model thing as a type of a Venn diagram. For those of you that are familiar with Venn diagrams, there are two circles that interlock. The one side is conventional medicine. The other side is alternative medicine. Conventional medicine is really, really good at acute issues. If you have an acute heart attack, acute stroke, you want to be at a hospital getting life saving anticoagulation therapy. The one thing that traditional medicine is not that great at, which a lot of the statistics show is chronic healthcare. Someone who already has diabetes, heart disease, fibromyalgia, chronic pain, peripheral neuropathy. How do you manage all these complicated issues that interlock or interwoven? Well, the alternative model looks at different things to help treat those that can actually help the patient, that are more focused on the patient. Where these two worlds meet. You have the conventional medicine with all your data and science. The alternative model looking at other traditions and where the data and the other traditions meet. Those nodes are the nodes of the functional medicine model. If you can imagine one big circle around all that, that would be holistic care, holistic integrative care. So you have this very comprehensive way of looking at an individual and their care. That is what integrative and functional medicine is.
So hopefully this introductory podcast was helpful.
To wrap your brain around this. Next time I'll be talking about diet, lifestyle, nutrition and other these basic key factors in individual's care and health.
We hope you found today's episode useful and informative. Please see the show notes on our website at www.richmondfunctionalmedicine.com. in addition to many other resources and educational materials, we'd also like to invite you to subscribe to our podcast to keep up to date with new episodes. You can find us on Apple Podcasts or wherever you listen to podcasts. Please also consider giving us a five star star rating and review so that others can gain access to this information. You can also find Richmond Integrative and Functional Medicine on Facebook and Instagram.
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