How Gut Bacteria Affect Estrogen Detox #shorts

28 Apr 2026 · 0 min
0:18

In this YouTube short, Dr. Aaron Hartman explains that certain gut bacteria produce the enzyme beta‑glucuronidase, which can interfere with the body’s normal estrogen detoxification pathways. When beta‑glucuronidase activity is elevated, estrogen may be re‑activated in the gut, contributing to estrogen dominance. Dr. Hartman notes that supplementing with calcium D‑glucarate—a compound that inhibits beta‑glucuronidase—can dramatically improve estrogen clearance, underscoring the gut microbiome’s pivotal role in hormonal balance.

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