A brief clinician-led talk by Aaron Hartman, MD describing how joint hypermobility can cause visceral ptosis (internal organs sagging), which impairs gut motility and promotes bacterial and yeast overgrowth (SIBO), potentially leading to increased intestinal permeability (‘leaky gut’) and a range of immune dysregulation. The speaker links these gut changes to higher rates of environmental and self-directed autoimmunity/allergic reactivity (asthma, allergies), skin conditions from microbial reactivity (eczema, rosacea), and loss of immune tolerance.
Chapters
Well, the first thing with hypermobility is you tend to get basically a thing called visceral optosis, or basically your internal organs kind of sink a little bit. That affects motility. It increases bacterial overgrowth, yeast overgrowth. And so what happens is it can actually, by itself induce a thing called leaky gut syndrome, or increased gastrointestinal permeability. So just having, you know, saggy bowels, so to speak, from your hypermobility can lead to more autoimmune issues. And what happens is your body loses tolerance to itself. Now, there's two major kinds of autoimmunity. Autoimmunity to environment, which we call allergies, and. And asthma. There's a reactivity to the bacteria on your skin, which we see as eczema. There's reactivity to yourself. These are all different forms of dysregulation, or abnormal reaction of your immune system. It's supposed to ignore 99.9% of everything that happens. Well, if it now starts reacting with dust, dust mites, pollen, you get respiratory tract issues, and you can react to yeast on your skin, staph on your skin. You can see really terrible eczema in kids. You can also see this in rosacea, where people actually get facial changes, acne, and it's basically caused by sibo dysbiosis in your gut.